Gene regulation and DNA damage in the ageing human brain
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- Type
- article
- Published
- 2004-06-24
- Cited by
- 1,894
- References
- 25
- OpenAlex
- https://openalex.org/W1979369962
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1867993
Keywords
Ageing, DNA repair, DNA damage, Biology, Gene
References
- Gene-expression profile of the ageing brain in mice
- Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA.
- DNA repair domains within a human gene: selective repair of sequences near the transcription initiation site.
- Development and field-test validation of an assay for DNA repair in circulating human lymphocytes.
- Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
- Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation.
- Genetics and the Specificity of the Aging Process
- Prolonged Ca2+-dependent afterhyperpolarizations in hippocampal neurons of aged rats.
- Gene expression profiling in Werner syndrome closely resembles that of normal aging
- Repair of endogenous DNA damage.
- Neuronal activity-dependent cell survival mediated by transcription factor MEF2.
- Cdk5 behind the wheel: a role in trafficking and transport?
- A century of cognitive decline
- Evolutionary Medicine: From Dwarf Model Systems to Healthy Centenarians?
- The Endocrine Regulation of Aging by Insulin-like Signals
- The effects of aging on gene expression in the hypothalamus and cortex of mice.
- Comparing genomic expression patterns across species identifies shared transcriptional profile in aging
- Effect of oxidative DNA damage in promoter elements on transcription factor binding.
- AMPA receptor trafficking and synaptic plasticity.
- Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain
Cited by
- Gestörte epigenetische Regulation als Angriffspunkt für neue Substanzen zur Behandlung von Demenzen und Psychosen
- Implication du BDNF dans l'étiopathogenèse et le traitement des troubles anxio-dépressifs : aspects précliniques.
- Brain aging phenomena in migrating sockeye salmon Oncorhynchus nerka nerka
- Decreased activity and increased aggregation of brain calcineurin during aging.
- Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.
- Different DNA repair strategies to combat the threat from 8-oxoguanine.
- Nucleic acid oxidation in Alzheimer disease.
- Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection
- Ultrahigh-throughput approach for analyzing single-cell genomic damage with an agarose-based microfluidic comet array.
- Cycle Checkpoint Abnormalities during Dementia: A Plausible Association with the Loss of Protection against Oxidative Stress in Alzheimer’s Disease
- Impact of aging on heat shock protein expression in the substantia nigra and striatum of the female rat
- Heritable changes in regional cortical thickness with age
- Noncoding Transcriptional Landscape in Human Aging.
- Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology?
- Age-associated Cognitive Decline: Insights into Molecular Switches and Recovery Avenues
- Epigenetics of memory and plasticity.
- Cognitive deficit in hippocampal‐dependent tasks in Werner syndrome mouse model
- The aging rat retina: from function to anatomy.
- Genome-wide mapping of 8-oxo-7,8-dihydro-2′-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells
- Structural insights into DNA replication and lesion bypass by Y family DNA polymerases
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