Amino acid substitution during functionally constrained divergent evolution of protein sequences.

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Summary

The matrices show that the genetic code influences accepted point mutations strongly at early stages of divergence, while the chemical properties of the side chains dominate at more advanced stages.

Type
article
Published
1994-11-01
Cited by
169
References
2
Access
Open access

Keywords

Point mutation, Amino acid, Sequence (biology), Genetic code, Mutation

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