Applying motif and profile searches.
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Summary
This chapter discusses the main strategies currently in use in applying motif and profile searches, making clear both their powers and pitfalls, and demonstrates their usage with two well-known domains as examples.
- Type
- article
- Published
- 1996-01-01
- Cited by
- 155
- References
- 39
- OpenAlex
- https://openalex.org/W1774728382
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9593149
Keywords
Motif (music), Computer science, Sequence homology, Sequence motif, Homology (biology)
References
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- Recognition of distantly related protein sequences using conserved motifs and neural networks.
- PH domain: the first anniversary.
Cited by
- Extracting protein alignment models from the sequence database.
- Comparison of ARM and HEAT protein repeats.
- Sequence and structural links between distant ADP-ribosyltransferase families.
- Janus Kinases and Focal Adhesion Kinases Play in the 4.1 Band: A Superfamily of Band 4.1 Domains Important for Cell Structure and Signal Transduction
- The identification of differentially expressed genes in sugarcane following infection with Fiji disease fijivirus.
- Purification, crystallisation and X-ray structure analysis of proteins from the lysine biosynthetic pathway of Mycobacterium tuberculosis and structural studies of membrane proteins from Deinococcus radiodurans R1 and Escherichia coli K12
- Pedestrian guide to analyzing sequence databases
- Protein Local Tertiary Structure Prediction by Super Granule Support Vector Machines with Chou-Fasman Parameter
- Sources of Systematic Error in Functional Annotation of Genomes: Domain Rearrangement, Non-Orthologous Gene Displacement and Operon Disruption
- Analysis of and function predictions for previously conserved hypothetical or putative proteins in Blochmannia floridanus
- Mathematically Complete Nucleotide and Protein Sequence Searching Using Ssearch
- More than 1,000 putative new human signalling proteins revealed by EST data mining
- Gene families: the taxonomy of protein paralogs and chimeras.
- Detection of DNA-binding helix-turn-helix motifs in proteins using the pattern dictionary method.
- Extraction of Protein Sequence Motifs Information by Bi-Clustering Algorithm
- A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins
- Evolution of domain families.
- Protein Structure Prediction using Coarse Grain Force Fields
- Towards protein function annotations for matching remote homologs
- dissectHMMER: a HMMER-based score dissection framework that statistically evaluates fold-critical sequence segments for domain fold similarity
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