SGP-1: prediction and validation of homologous genes based on sequence alignments.
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Summary
A program for the prediction of protein-coding genes, termed SGP-1 (Syntenic Gene Prediction), which is based on the similarity of homologous genomic sequences, which may be applied to nonstandard model organisms in vertebrates as well as in plants, without the need for extensive parameter training.
- Type
- article
- Published
- 2001-09-01
- Cited by
- 108
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W1977828801
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22977921
Keywords
Biology, Gene prediction, Synteny, Gene, Computational biology
References
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- Evaluation of gene structure prediction programs.
- Computational methods for exon detection
- Chaining multiple-alignment fragments in sub-quadratic time
- Genome Sequence Comparisons: Hurdles in the Fast Lane to Functional Genomics
- A time-efficient, linear-space local similarity algorithm
- Rates of DNA sequence evolution differ between taxonomic groups.
- Basic local alignment search tool.
- A general method applicable to the search for similarities in the amino acid sequence of two proteins.
- Finding the genes in genomic DNA.
- The origins of genomic duplications in Arabidopsis.
- Assembling Genes from Predicted Exons in Linear Time with Dynamic Programming
- The Conserved Exon Method for Gene Finding
- The Complete Sequence of 340 kb of DNA around the Rice Adh1–Adh2 Region Reveals Interrupted Colinearity with Maize Chromosome 4
- DNA sequence evolution: the sounds of silence.
- Alignment of whole genomes.
Cited by
- Classification d'ARN codants et d'ARN non-codants
- AGenDA: Gene Prediction by Comparative Sequence Analysis
- Comparative analysis of eukaryotic gene sequence features
- The integration of sequencing and bioinformatics in metagenomics
- Comparative Genomics
- NovelFam3000 – Uncharacterized human protein domains conserved across model organisms
- PipMaker: A World Wide Web Server for Genomic Sequence Alignments
- Approaches to Fungal Genome Annotation
- Applied bioinformatics for gene characterization
- The Retinome – Defining a reference transcriptome of the adult mammalian retina/retinal pigment epithelium
- Gene annotation: prediction and testing.
- CSAM: Using Clustering-Hashing-Signal Anchoring Method to Explore Human Novel Genes
- Comparative genomics: genome-wide analysis in metazoan eukaryotes
- The computational challenges of applying comparative-based computational methods to whole genomes
- Plant evolutionary genomics.
- Global predictions and tests of erythroid regulatory regions.
- Comparative genomics of Dictyostelium discoideum and Entamoeba histolytica.
- Valid: Validation of Protein Sequence Quality Based on Multiple Alignment Data
- AGenDA: gene prediction by cross-species sequence comparison
- Computational prediction of eukaryotic protein-coding genes
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