Quantification of Ten Neuroactive Steroids in Plasma in Withdrawal Seizure–Prone and –Resistant Mice During Chronic Ethanol Withdrawal
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Summary
It is possible that the combined decrease in neuroactive steroids and GABAAR sensitivity during ethanol withdrawal in WSP-1 mice represents a neurochemical substrate for severe ethanol withdrawal.
- Type
- article
- Published
- 2014-05-29
- Cited by
- 21
- References
- 51
- Access
- Open access
- OpenAlex
- https://openalex.org/W1977660693
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3194425
Keywords
Neuroactive steroid, Pregnanolone, Allopregnanolone, Endocrinology, Internal medicine
References
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Cited by
- Antiseizure Activity of Midazolam in Mice Lacking δ-Subunit Extrasynaptic GABAA Receptors
- Sex Differences in Ethanol’s Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice With a Null Mutation of the 5α-Reductase Type 1 Gene
- ¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.
- Ethanol Withdrawal-Induced Dysregulation of Neurosteroid Levels in Plasma, Cortex, and Hippocampus in Genetic Animal Models of High and Low Withdrawal
- Role of GABAA receptors in alcohol use disorders suggested by chronic intermittent ethanol (CIE) rodent model
- Chapter X. Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol
- Rehabilitation of Infant Oral Feeding Difficulties: A Survey of Occupational Therapists Practice Approaches
- The Cerebellar GABAAR System as a Potential Target for Treating Alcohol Use Disorder
- Genotype Differences in Sensitivity to the Anticonvulsant Effect of the Synthetic Neurosteroid Ganaxolone During Chronic Ethanol Withdrawal
- Sexually divergent changes in select brain proteins and neurosteroid levels after a history of ethanol drinking and intermittent PTSD-like stress exposure in adult C57BL/6J mice
- Chronic ethanol drinking increases during the luteal menstrual cycle phase in rhesus monkeys: implication of progesterone and related neurosteroids
- Stress and drug abuse-related disorders: the promising therapeutic value of neurosteroids Focus on Pregnenolone-Progesterone-Allopregnanolone pathway.
- TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity
- A Rationale for Allopregnanolone Treatment of Alcohol Use Disorders: Basic and Clinical Studies
- (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) regulation of hypothalamic and extrahypothalamic corticotropin releasing factor (CRF): Sexual dimorphism and brain region specificity in Sprague Dawley rats
- Genetic and genomic signatures in ethanol withdrawal seizure-prone and seizure-resistant mice implicate genes involved in epilepsy and neuronal excitability.
- Brexanolone therapeutics in post-partum depression involves inhibition of systemic inflammatory pathways
- Stress and Gonadal Steroid Influences on Alcohol Drinking and Withdrawal, with Focus on Animal Models in Females
- GABAergic Neuroactive Steroid Response to Sertraline in Premenstrual Dysphoric Disorder
- Luteal Phase Sertraline Treatment of Premenstrual Dysphoric Disorder (PMDD): Effects on Markers of Hypothalamic Pituitary Adrenal (HPA) Axis Activation and Inflammation
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