Genomic Relationships and Speciation Times of Human, Chimpanzee, and Gorilla Inferred from a Coalescent Hidden Markov Model

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Summary

A hidden Markov model that incorporates genealogical variation and relates the model parameters to population genetics quantities such as speciation times and ancestral population sizes finds that the rate of transitions between different genealogies correlates well with the region-wide present-day human recombination rate, but does not correlate with the fine-scale recombination rates and recombination hot spots.

Type
article
Published
2006-11-30
Cited by
334
References
34
Access
Open access

Keywords

Coalescent theory, Biology, Gorilla, Evolutionary biology, Genetic algorithm

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