ACE2: a new target for cardiovascular disease therapeutics.
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Summary
The role of ACE2 in the cardiovascular system is summarized, the importance ofACE2-Ang-(1-7) axis in the control of normal cardiovascular physiology and ACE2 as a potential target in the development of novel therapeutic agents for cardiovascular diseases are discussed.
- Type
- review
- Published
- 2007-08-01
- Cited by
- 165
- References
- 103
- OpenAlex
- https://openalex.org/W1977150613
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:29396397
Keywords
Angiotensin-converting enzyme 2, Renin–angiotensin system, Neprilysin, Enzyme, Angiotensin 1
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Cited by
- Mass spectrometry for the molecular imaging of angiotensin metabolism in kidney.
- Angiotensin-(1-7) Augments Endothelium-dependent Relaxations of Porcine Coronary Arteries to Bradykinin by Inhibiting Angiotensin-Converting Enzyme 1
- The Relationship of Basic Conditioning Factors, Knowledge, Self-care Agency, Self-care Behavior, and Urinary Sodium Excretion of Hypertensive Older Adults: Testing Orem’s Self-Care Theory
- Current research of the RAS in pancreatitis and pancreatic cancer.
- Respiratory Regulation - The Molecular Approach
- INTERAÇÃO ENTRE A ANGIOTENSINA II, ANGIOTENSINA-(1-7) E ECA2 EM MULHERES.
- Mammalian and viral protease inhibitors
- The Concise Guide to Pharmacology 2013/14: Enzymes
- AVE 0991, a non‐peptide Mas‐receptor agonist, facilitates penile erection
- Injections of angiotensin‐converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats
- Angiotensin converting enzyme 2: A new important player in the regulation of glycemia
- Caracterização de um sistema renina-angiotensina local no tecido gengival de rato
- ATIVIDADE DA ENZIMA CONVERSORA DE ANGIOTENSINA E OS NÍVEIS PLASMÁTICOS DE PEPTÍDEOS DO SISTEMA RENINA-ANGIOTENSINA (ANG I, ANG II E ANG-(1-7)) EM MULHERES NORMOTENSAS E HIPERTENSAS NO CLIMATÉRIO
- Identification of the Metabolites of Angiotensin II (1-8) in MES-13 Cells by a Simple NanoLC-MS-MS System: A Preliminary Platform
- A biodegradable porous composite scaffold of PCL/BCP containing Ang-(1-7) for bone tissue engineering
- Viral infection and human disease--insights from minimotifs.
- Angiotensin-converting enzyme 2 acts as a potential molecular target for pancreatic cancer therapy.
- Propofol Increases Angiotensin-Converting Enzyme 2 Expression in Human Pulmonary Artery Endothelial Cells
- A lifetime of aldosterone excess: long-term consequences of altered regulation of aldosterone production for cardiovascular function.
- Cerebroprotective Action of Angiotensin Peptides in Stroke
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