Galantamine attenuates the heroin seeking behaviors induced by cues after prolonged withdrawal in rats.
Explore this paper's citation graph
Summary
It is suggested that cholinergic transmission in the LDT may play a critical role in heroin-seeking behavior induced by cues and that galantamine may have the beneficial effect of blocking heroin- seeking behavior, which is mediated through its actions on the muscarinic receptors.
- Type
- article
- Published
- 2012-06-01
- Cited by
- 25
- References
- 38
- OpenAlex
- https://openalex.org/W1975708397
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12967679
Keywords
Galantamine, Heroin, Pharmacology, Psychology, Nucleus accumbens
References
- Differential involvement of the prelimbic cortex and striatum in conditioned heroin and sucrose seeking following long‐term extinction
- Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats
- Multiple Muscarinic Acetylcholine Receptor Subtypes Modulate Striatal Dopamine Release, as Studied with M1–M5 Muscarinic Receptor Knock-Out Mice
- M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related central nervous system pathologies
- Rewarding Effects of the Cholinergic Agents Carbachol and Neostigmine in the Posterior Ventral Tegmental Area
- Suppression of methamphetamine-seeking behavior by nicotinic agonists.
- A range of research-based pharmacotherapies for addiction.
- Increased striatal dopamine efflux follows scopolamine administered systemically or to the tegmental pedunculopontine nucleus.
- Role of acetylcholine transmission in nucleus accumbens and ventral tegmental area in heroin-seeking induced by conditioned cues.
- The role of withdrawal in heroin addiction: enhances reward or promotes avoidance?
- Galantamine Enhances Dopaminergic Neurotransmission In Vivo Via Allosteric Potentiation of Nicotinic Acetylcholine Receptors
- Glutamate Release in the Nucleus Accumbens Core Is Necessary for Heroin Seeking
- Motivational control of heroin seeking by conditioned stimuli associated with withdrawal and heroin taking by rats.
- Muscarinic type 2 receptors in the lateral dorsal tegmental area modulate cocaine and food seeking behavior in rats
- Midbrain acetylcholine and glutamate receptors modulate accumbal dopamine release
- Basolateral amygdala inactivation abolishes conditioned stimulus- and heroin-induced reinstatement of extinguished heroin-seeking behavior in rats
- Effects of training and withdrawal periods on heroin seeking induced by conditioned cue in an animal of model of relapse
- Galantamine improves cognition in schizophrenic patients stabilized on risperidone.
- Activation of Muscarinic and Nicotinic Acetylcholine Receptors in the Nucleus Accumbens Core Is Necessary for the Acquisition of Drug Reinforcement
- Laterodorsal tegmental stimulation elicits dopamine efflux in the rat nucleus accumbens by activation of acetylcholine and glutamate receptors in the ventral tegmental area
Cited by
- The phosphodiesterase-4 inhibitor rolipram attenuates heroin-seeking behavior induced by cues or heroin priming in rats.
- Influence of cholinesterase inhibitors, donepezil and rivastigmine on the acquisition, expression, and reinstatement of morphine-induced conditioned place preference in rats.
- Blockade of mGluR5 in the nucleus accumbens shell but not core attenuates heroin seeking behavior in rats
- Low dose risperidone attenuates cue-induced but not heroin-induced reinstatement of heroin seeking in an animal model of relapse.
- [Cognitive impairments in psychoactive drug addicts].
- Role of opioid receptors in the reinstatement of opioid-seeking behavior: an overview.
- Acquisition and reinstatement of ethanol-induced conditioned place preference in rats: Effects of the cholinesterase inhibitors donepezil and rivastigmine
- Effects of histone deacetylase inhibitor sodium butyrate on heroin seeking behavior in the nucleus accumbens in rats.
- The effect of interference with muscarinic receptor on drug addiction and its relationship with dopamine
- Muscarinic receptors in the nucleus accumbens shell play different roles in context‐induced or morphine‐challenged expression of behavioral sensitization in rats
- Relapse to opioid seeking in rat models: behavior, pharmacology and circuits
- Cognitive enhancers as a treatment for heroin relapse and addiction
- Double blind placebo-controlled trial of galantamine for methadone-maintained individuals with cocaine use disorder: Secondary analysis of effects on illicit opioid use
- A novel therapeutic for opioid use disorder targeting the cholinergic system
- Randomized Placebo-Controlled Trial of Galantamine in Individuals with Cocaine Use Disorder
- Ameliorative effect of galantamine on acetic acid-induced colitis in rats
- Huperzine A inhibits heroin-seeking behaviors induced by cue or heroin priming in rats
- Role of nucleus accumbens microRNA-181a and MeCP2 in incubation of heroin craving in male rats
- Opioid Receptors
- Cognitive Enhancer Donepezil Attenuates Heroin-Seeking Behavior Induced by Cues in Rats.
Related papers
- Mecamylamine interactions with galantamine and donepezil: effects on learning, acetylcholinesterase, and nicotinic acetylcholine receptors.
- An EEG nicotinic acetylcholine index to assess the efficacy of pro-cognitive compounds.
- Nicotinic component of galantamine in the regulation of amyloid precursor protein processing.
- Positive allosteric modulators of alpha 7 nicotinic acetylcholine receptors enhance procognitive effects of conventional anti-Alzheimer drugs in scopolamine-treated rats.
- Time Course, Behavioral Safety, and Protective Efficacy of Centrally Active Reversible Acetylcholinesterase Inhibitors in Cynomolgus Macaques
- Pharmacokinetic rationale for switching from donepezil to galantamine.
- Galantamine nanoparticles outperform oral galantamine in an Alzheimer's rat model: pharmacokinetics and pharmacodynamics.
- Cholinergic modulation of mesolimbic dopamine function and reward