Signaling through the Death Receptor CD95 (APO-1/FAS)

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Summary

Caspase-8 plays an essential role in the execution of death receptor-mediated apoptosis by proteolytical cleavage into the prodomain containing two death effector domains (DED) and two active subunits, p18 and p10 (4).

Type
article
Published
2001-12-01
Cited by
0
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Open access

Keywords

FADD, Death domain, Fas receptor, Caspase 8, Cell biology

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