The Ames Salmonella/microsome mutagenicity assay.
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Summary
Historical aspects of how the Ames test was developed and detailed procedures for performing the test, including the design and interpretation of results are provided, to determine the mutagenic potential of new chemicals and drugs.
- Type
- review
- Published
- 2000-11-20
- Cited by
- 2,041
- References
- 99
- OpenAlex
- https://openalex.org/W1973879072
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8803035
Keywords
Ames test, Salmonella, Histidine, Mutagen, Microsome
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- UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test.
- Mutagenicity of Airborne Particulates Assessed by Salmonella Assay and the SOS Chromotest in Wrocław, Poland
- Genotoxicity evaluation of Mequindox in different short-term tests.
- Photoelectrocatalysis based on Ti/TiO2 nanotubes removes toxic properties of the azo dyes Disperse Red 1, Disperse Red 13 and Disperse Orange 1 from aqueous chloride samples.
- Anti-mutagenicity Effects of Vitamin E on Oncology and Non-oncology Hospital Nurses by Ames Assay.
- Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention
- Further evidence on the favorable role of the anomeric effect on the cleavage of HepDirect and cyclophosphamide prodrugs.
- Eco- and Genotoxicological Assessments of Two Reactive Textile Dyes
- Comparative Study of Genotoxicity Induced by Six Different PBDEs
- Lanthanum nitrate genotoxicity evaluation: Ames test, mouse micronucleus assay, and chromosome aberration test.
- Genotoxicity of metal based engineered nanoparticles in aquatic organisms: A review.
- Genotoxicity assessment of calcium &bgr;‐hydroxy‐&bgr;‐methylbutyrate
- The use of marine bacteria in mutagenicity assays.
- eToxPred: a machine learning-based approach to estimate the toxicity of drug candidates
- Assessment of antioxidant / anticarcinogenic activity of plant extracts by a combination of molecular methods.
- Bacterial mutation assays.
- Efeitos do composto 3'3-ditrifluormetildifenil disseleneto em diferentes modelos biológicos
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