Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

Explore this paper's citation graph

Summary

Elderly study participants were markedly insulin-resistant as compared with young controls, and this resistance was attributable to reduced insulin-stimulated muscle glucose metabolism, which supports the hypothesis that an age-associated decline in mitochondrial function contributes to insulin resistance in the elderly.

Type
article
Published
2003-05-16
Cited by
2,145
References
30
Access
Open access

Keywords

Insulin resistance, Internal medicine, Endocrinology, Insulin, Oxidative phosphorylation

References

Cited by

Related papers