Evaluation of the effect of BAL (2,3-dimercaptopropanol) on arsenite-induced teratogenesis in mice.
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Summary
BAL is unlikely to have a practical beneficial effect on the arsenite exposed conceptus, because it must be administered prior to the teratogen to be effective, although an apparent decrease in gross and skeletal malformation was suggestive of such an effect.
- Type
- article
- Published
- 1984-03-30
- Cited by
- 23
- References
- 19
- OpenAlex
- https://openalex.org/W1973822251
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25636445
Keywords
Arsenite, Sodium arsenite, Conceptus, Toxicity, Teratology
References
- Arsenic-induced axial skeletal (dysraphic) disorders.
- Effects of sodium arsenite on fetal development
- BAL alleviation of arsenate-induced teratogenesis in mice.
- Toxicity of metals to chick embryos
- Protection of mice against the lethal effects of sodium arsenite by 2,3 dimercapto-1-propane-sulfonic acid and dimercaptosuccinic acid.
- Prenatal toxicity of orally administered sodium arsenite in mice
- Interrelationships of selenium, cadmium, and arsenic in mammalian teratogenesis.
- Malformations induced by sodium arsenate.
- Teratogenic effects of sodium arsenate in mice.
- Acute maternal arsenic intoxication with neonatal death.
- Developmental anomalies in mice induced by 2,3‐dimercaptopropanol (BAL)
- Prevention by tiopronin (2-mercaptopropionyl glycine) of methylmercuric chloride-induced teratogenic and fetotoxic effects in mice.
- Occupational and environmental risks in and around a smelter in northern Sweden. III. Frequencies of spontaneous abortion.
- The use of British anti-lewisite containing radioactive sulphur for metabolism investigations.
- Effect of trivalent and pentavalent arsenic on early developmental stages of the chick embryo.
- Further investigations on the metabolism of 2:3-dimercaptopropanol.
- Heavy metal antagonists
Cited by
- Effects of meso-2,3-dimercaptosuccinic acid (DMSA) on the teratogenicity of sodium arsenate in mice
- Inorganic arsenic compounds: are they carcinogenic, mutagenic, teratogenic?
- An assessment of the developmental toxicity of inorganic arsenic.
- Prevention by Tiron (sodium 4,5-dihydroxybenzene-1,3-disulfonate) of vanadate-induced developmental toxicity in mice.
- Appropriate use of animal models in the assessment of risk during prenatal development: an illustration using inorganic arsenic.
- Effectiveness of sodium 4,5-dihydroxybenzene-1,3-disulfonate (Tiron) in protecting against uranium-induced developmental toxicity in mice.
- Developmental and reproductive toxicity of inorganic arsenic: animal studies and human concerns.
- Metal-induced developmental toxicity in mammals: a review.
- Amelioration by BAL (2,3-dimercapto-1-propanol) and DMPS (sodium 2,3-dimercapto-1-propanesulfonic acid) of arsenite developmental toxicity in mice.
- Developmental toxicity of metal chelating agents.
- Interactions in developmental toxicology: a literature review and terminology proposal.
- Prevention by chelating agents of metal-induced developmental toxicity.
- Evaluation of the protective activity of 2,3-dimercaptopropanol and sodium 2,3-dimercaptopropane-1-sulfonate on methylmercury-induced developmental toxicity in mice
- Acute and chronic arsenic toxicity
- meso-2,3-Dimercaptosuccinic acid and prevention of arsenite embryotoxicity and teratogenicity in the mouse.
- Appropriate Exposure Routes and Doses in Studies Designed to Assess Developmental Toxicity: A Case Study of Inorganic Arsenic
- Arsenic Toxicity and Neurobehaviors : A Review
- MEDICAL AND BIOLOGICAL ASPECTS RELATED TO ASSESSMENT OF IMPACTS EXERTED BY RISK FACTORS
- PUBLIC HEALTH GOALS FOR CHEMICALS IN DRINKING WATER URANIUM
- Metal-induced developmental toxicity in mammals
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