The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood
Explore this paper's citation graph
Summary
It is demonstrated that CpGs are differentially methylated dependent upon the genomic features of the sequence in which they are embedded, and that C pG methylation is associated with age and hair dye use in a CpG context-dependent manner in healthy individuals.
- Type
- article
- Published
- 2011-07-01
- Cited by
- 58
- References
- 60
- Access
- Open access
- OpenAlex
- https://openalex.org/W1973778874
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45922170
Keywords
DNA methylation, CpG site, Biology, Epigenetics, Methylation
References
- W. H. Fox Talbot and the history of photography
- Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
- DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker.
- Decline in Genomic DNA Methylation through Aging in a Cohort of Elderly Subjects
- DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project
- Hair-color products and risk for non-Hodgkin's lymphoma: a population-based study in the San Francisco bay area.
- Identification of disease‐associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease
- Safety assessment of personal care products/cosmetics and their ingredients.
- DNA hypomethylation and human diseases.
- A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci
- Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
- Occupational, environmental, and life-style factors associated with the risk of hematolymphopoietic malignancies in women.
- Global, comparative analysis of tissue-specific promoter CpG methylation.
- Smoking modifies the relationship between XRCC1 haplotypes and HPV16-negative head and neck squamous cell carcinoma
- Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA.
- Comprehensive analysis of CpG islands in human chromosomes 21 and 22
- DNA methylation and cancer.
- Alterations of c-fos gene methylation in the processes of aging and tumorigenesis in human liver.
- Age-dependent alterations in mRNA level and promoter methylation of collagen alpha1(I) gene in human periodontal ligament.
- The role of epigenetics in aging and age-related diseases.
Cited by
- Inflammation, advancing age and nutrition
- An investigation of epigenetic contributions to inter-animal and age dependent variation in the bovine innate immune response
- Host Factors and Risk of Breast Cancer Recurrence: Genetic, Epigenetic and Biologic Factors and Breast Cancer Outcomes.
- LINE-1 DNA Methylation, Smoking and Risk of Parkinson’s Disease
- Factors underlying variable DNA methylation in a human community cohort
- Aging epigenetics: causes and consequences.
- Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships
- Recommendations for the design and analysis of epigenome-wide association studies
- Influence of environmental exposure on human epigenetic regulation
- Interindividual variability and co-regulation of DNA methylation differ among blood cell populations
- Identification of an Epigenetic Profile Classifier That Is Associated with Survival in Head and Neck Cancer
- Fetal epigenetic programming of adipokines
- Epigenetics and the environment: emerging patterns and implications
- Genome-wide DNA methylation variability in adolescent monozygotic twins followed since birth
- From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
- Childhood Adversity and Epigenetic Modulation of the Leukocyte Glucocorticoid Receptor: Preliminary Findings in Healthy Adults
- Genetic and epigenetic predictors of responsiveness to treatment in RA
- An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis.
- Postnatal development- and age-related changes in DNA-methylation patterns in the human genome
- Epigenomics in Environmental Health
Related papers
- Genetic and environmental impacts on DNA methylation levels in twins.
- DNA methylation in osteoarthritic chondrocytes: a new molecular target.
- Early Nutritional Influences on Human Developmental Epigenetics.
- Changes of DNA methylation of Isoetes sinensis under Pb and Cd stress
- Methylation of CpG sites in BCL2 major breakpoint region and the increase of BCL2/JH translocation with aging
- Global methylation profiles in DNA from different blood cell types
- Progressive age-dependent DNA methylation changes start before adulthood in mouse tissues.
- New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development
- Predicting the progress of colon cancer by DNA methylation markers of the p16 gene in feces - Evidence from an animal model