The gateway to transcription: identifying, characterizing and understanding promoters in the eukaryotic genome
Explore this paper's citation graph
Summary
Recent experimental and computational advances that have enabled the identification and analysis of transcriptional promoters on an unprecedented scale are reviewed, laying a foundation for systematic determination of the transcriptional regulatory networks in eukaryotic cells.
- Type
- review
- Published
- 2007-02-01
- Cited by
- 114
- References
- 121
- Access
- Open access
- OpenAlex
- https://openalex.org/W1972813594
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21763499
Keywords
Promoter, Computational biology, Biology, Transcriptional regulation, Chromatin
References
- Yeast transcriptional regulatory mechanisms.
- Regulatory diversity among metazoan co-activator complexes
- Content Analysis of the Core Promoter Region of Human Genes
- Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter
- Organization and expression of eucaryotic split genes coding for proteins.
- Structure and mechanism of the RNA polymerase II transcription machinery
- Promoter prediction analysis on the whole human genome
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
- Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.
- Global and Hox-specific roles for the MLL1 methyltransferase.
- Genomic characterization reveals a simple histone H4 acetylation code.
- Patterning chromatin: form and function for H2A.Z variant nucleosomes.
- Evidence for nucleosome depletion at active regulatory regions genome-wide
- Decoding the nucleosome.
- Reading signals on the nucleosome with a new nomenclature for modified histones
- Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IID.
- The DPE, a core promoter element for transcription by RNA polymerase II
- The dynamics of chromatin remodeling at promoters.
- The language of covalent histone modifications
- Gene regulation by microRNAs.
Cited by
- Identification of Relevant Protein-Gene Associations by Integrating Gene Expression Data and Transcriptional Regulatory Networks.
- Genome-wide occupancy analysis by ChIP-chip and ChIP-Seq.
- Analysis of Developmental Epistasis by Chromatin Immunoprecipitation in Xenopus laevis
- Evolution des génomes microsporidiens et mécanisme d'adaptation moléculaire chez les parasites intracellulaires obligatoires
- Regulators of chromatin and transcription in Drosophila
- Functional consequences of the direct physical interaction between E2A transcription factors and CBP/p300
- Investigating venom synthesis: exploring the composition, variation and gene expression dynamics of Bitis arietans venom
- Estudi del factor de transcripció Cabut en el desenvolupament i la regeneració de Drosophila melanogaster
- Transcriptional and post-transcriptional gene regulatory mechanisms in the malaria parasite, Plasmodium falciparum
- Transcription et épissage des gènes d’immunoglobulines non-productifs : étude des mécanismes mis en jeu et de leur influence au cours du développement des lymphocytes B
- Structure-Function Analysis of the Drosophila melanogaster Caudal Transcription Factor Provides Insights into Core Promoter-preferential Activation*
- Unique and unifying themes in the mechanisms regulating the expression of the arabidopsis thaliana PR-1 and Solanum tuberosum PR-10a inducible defense genes
- Cellular Targeting for Cochlear Gene Therapy
- Studying histone modifications and their genomic functions by employing chromatin immunoprecipitation and immunoblotting.
- FUNCTION OF CORE PROMOTERS IN DIFFERENTIAL GENE REGULATION DURING EMBRYOGENESIS
- Cloning and characterization of the Iron-Regulated Transporter (IRT) genes and their transcription factors in Populus
- Patterns and Complexity in Biological Systems: A Study of Sequence Structure and Ontology-based Networks
- ElemeNT: a computational tool for detecting core promoter elements
- The core promoter: At the heart of gene expression.
- Genome-wide analysis of the relationships between DNaseI HS, histone modifications and gene expression reveals distinct modes of chromatin domains
Related papers
- The origins of developmental gene regulation
- Identify gene expression pattern change at transcriptional and post-transcriptional levels
- RNA-mediated gene regulation is less evolvable than transcriptional regulation
- Complex transcriptional regulation of myc family gene expression in the developing mouse brain and liver
- Post-transcriptional control by global regulators of gene expression in bacteria.
- Computational Identification of Transcriptional Regulators in Human Endotoxemia
- ADGR: Admixture-Informed Differential Gene Regulation
- Review: transcriptional and post-transcriptional regulation of interleukin 1 gene expression.