The Role of Single-stranded DNA and Polymerase α in Establishing the ATR, Hus1 DNA Replication Checkpoint*

Keywords

Chromatin, Control of chromosome duplication, Origin recognition complex, Eukaryotic DNA replication, Biology

References

• The Schizosaccharomyces pombe rad3 checkpoint gene.Nicola J. Bentley, Douglas A. Holtzman, Gail Flaggs — 1996
• Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1Yan Zeng, Kristi Chrispell Forbes, Zhiqi Wu — 1998
• The DNA damage response: putting checkpoints in perspectiveBin‐Bing S. Zhou, Stephen J. Elledge — 2000
• Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice.Hiroyuki Takai, Kaoru Tominaga, Noboru Motoyama — 2000
• ATR and ATRIP: Partners in Checkpoint SignalingDavid Cortez, Saritha Guntuku, Jun Qin — 2001
• A sliding clamp model for the Rad1 family of cell cycle checkpoint proteins.Michael P. Thelen, Česlovas Venclovas, Krzysztof Fidelis — 1999
• Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha.Johannes C. Walter, John W. Newport — 2000
• Human Homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 Form a DNA Damage-responsive Protein Complex*Elias Volkmer, Larry M. Karnitz — 1999
• Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice.Annelies de Klein, Manja Muijtjens, Ronald van Os — 2000
• The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1.Robert P. St.Onge, Christian M. Udell, Richard Casselman — 1999
• Checkpoints: controls that ensure the order of cell cycle events.Leland H. Hartwell, Ted Weinert — 1989
• Cdc2 regulatory factors.Thomas R. Coleman, William G. Dunphy — 1994
• Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct MechanismsTae Kondo, Tatsushi Wakayama, Takahiro Naiki — 2001
• A novel Rad24 checkpoint protein complex closely related to replication factor C.Catherine Green, Hediye Erdjument‐Bromage, Paul Tempst — 2000
• Cell Cycle Checkpoints: Preventing an Identity CrisisStephen J. Elledge — 1996
• cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein.Karlene A. Cimprich, Taehwan Shin, Curtis T. Keith — 1996
• Reconstitution and Molecular Analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA Damage Responsive Checkpoint Complex*Matthew A. Burtelow, Pia Roos‐Mattjus, Matthew P. Rauen — 2001
• Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.Ted Weinert, Gretchen Kiser, Leland H. Hartwell — 1994
• Mitotic DNA damage and replication checkpoints in yeast.Nick Rhind, Paul Russell — 1998
• Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin.Lee Zou, David Cortez, Stephen J. Elledge — 2002

Cited by

• The Yin Yang-1 (YY1) protein undergoes a DNA-replication-associated switch in localization from the cytoplasm to the nucleus at the onset of S phasePhil Evans, Terence J. Wilkin, Jinny Jeffery — 2003
• The DNA damage checkpoint response to replication stress: A Game of ForksRachel Jossen, Rodrigo Bermejo — 2013
• Análisis del papel de los componentes de la ruta RAD6/RAD18 de Saccharomyces cerevisiae en la tolerancia al daño en el DNA durante la replicación cromosómicaOrtiz Bazán, M. Ángeles — 2014
• Reviews and model systemsAxel H. Schönthal — 2004
• Recruitment of ATR-ATRIP, Rad17, and 9-1-1 complexes to DNA damage.Xiaohong Yang, Lee Zou — 2006
• Xenopus laevis as a model system for evaluating the function of fanconi anemia proteinsStacie Stone — 2008
• Analysis of Rad9 Functions; Roles in the Checkpoint Response, DNA Damage Processing, and Prevention of Genomic InstabilityKara A. Nyberg, Ted Weinert — 2003
• hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation.Deborah Greer, Blair D.A. Besley, Katherine B Kennedy — 2003
• Early events in the DNA damage response.Irene M. Ward, Junjie Chen — 2004
• Mammalian DNA damage response pathway.Zhenkun Lou, Junjie Chen — 2005
• Chk1 in the DNA damage response: conserved roles from yeasts to mammals.Yinhuai Chen, Yolanda Sánchez — 2004
• Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex.Edgardo R. Parrilla-Castellar, Sonnet J.H. Arlander, Larry M. Karnitz — 2004
• How Cells Activate ATRAkiko Kumagai, William G. Dunphy — 2006
• Hsp90 Inhibition Depletes Chk1 and Sensitizes Tumor Cells to Replication Stress*Sonnet J.H. Arlander, Alex Eapen, Benjamin T. Vroman — 2003
• ATR: An Essential Regulator of Genome IntegrityKarlene A. Cimprich, David Cortez — 2008
• The phosphorylated C‐terminal domain of Xenopus Cut5 directly mediates ATR‐dependent activation of Chk1Yoshitami Hashimoto, Tsuyoshi Tsujimura, Akio Sugino — 2006
• DNA replication: a complex matterIsabelle Frouin, Alessandra Montecucco, Silvio Spadari — 2003
• A splicing mutation affecting expression of ataxia–telangiectasia and Rad3–related protein (ATR) results in Seckel syndromeMark O’Driscoll, Víctor L. Ruiz‐Pérez, C. Geoffrey Woods — 2003
• Role of replication protein A as sensor in activation of the S-phase checkpoint in Xenopus egg extractsBénédicte Recolin, Siem van der Laan, Domenico Maiorano — 2011
• Probing ATR Activation with Model DNA TemplatesKarlene A. Cimprich — 2007

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