Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.

Keywords

Neprilysin, Neuroscience, Morris water navigation task, Downregulation and upregulation, Alzheimer's disease

References

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Cited by

• Drosophila Models of Alzheimer's Amyloidosis: The Challenge of Dissecting the Complex Mechanisms of Toxicity of Amyloid-β 42J.M. Fahley — 2008
• Convection-Enhanced Delivery of Neprilysin: A Novel Amyloid-β-Degrading Therapeutic StrategyC. Tonin, Franco Ferrero, S. Chiaverina — 2012
• Plasma insulin-degrading enzyme: Characterisation and evaluation as a potential biomarker for Alzheimer's diseaseMichelle Tegg — 2014
• Impact of Insulin Resistance on Behavioral and Neurochemical Deficits in db/db MiceAjaykumar N. Sharma — 2011
• Functional interactions between peroxisome proliferator-activated receptor-gamma and polipoprotein E isoforms in the regulation of neural functions in models of insulin resistance-relevance to Alzheimer's diseaseA. To — 2012
• Neprilysin Deficiency Alters the Neuropathological and Behavioral Phenotype in the 5XFAD Mouse Model of Alzheimer's DiseaseMelanie Hüttenrauch, Sandra Baches, Janina Gerth — 2015
• Recombinant AAV gene therapy and delivery for Alzheimer's diseaseNikisha Carty — 2009
• Neprilysin-Like Activity Correlates with CSF-Tau and Phospho-Tau in Patients with Alzheimer's DiseaseKatrine Christa Nordskov Sorensen, Anja Hviid Simonsen, Ulla Bachmann Holmetoft — 2013
• Convection‐Enhanced Drug Delivery to the Brain: Therapeutic Potential and Neuropathological ConsiderationsNeil U. Barua, Steven S. Gill, Seth Love — 2014
• A Butyrolactone Derivative 3BDO Alleviates Memory Deficits and Reduces Amyloid-β Deposition in an AβPP/PS1 Transgenic Mouse ModelLiFei Wei, Hui Yang, Zhaohong Xie — 2012
• Type 2 Diabetes as a Protein Misfolding DiseaseAbhisek Mukherjee, Diego Morales‐Scheihing, Peter C. Butler — 2015
• Binding of Proteases to Fibrillar Amyloid-β Protein and its Inhibition by Congo RedHarish Chander, Abha Chauhan, Ved Chauhan — 2007
• Neprilysin gene transfer: A promising therapeutic approach for Alzheimer's diseaseYuanli Li, Junqing Wang, Shenghao Zhang — 2015
• Novel targets for Alzheimer's disease treatmentJoshua D. Grill, Jeffrey L. Cummings — 2010
• Neprilysin Is Poorly Expressed in the Prefrontal Cortex of Aged Dogs with Cognitive Dysfunction SyndromeJesús Canudas, Daniel Insua, Leticia Sarasa — 2014
• Circulating Neprilysin Clears Brain AmyloidYinxing Liu, Christa M. Studzinski, Tina L. Beckett — 2010
• Neprilysin Overexpression Inhibits Plaque Formation But Fails to Reduce Pathogenic Aβ Oligomers and Associated Cognitive Deficits in Human Amyloid Precursor Protein Transgenic MiceWilliam J. Meilandt, Moustapha Cissé, Kaitlyn Ho — 2009
• Alzheimer disease models and human neuropathology: similarities and differencesCharles Duyckaerts, Marie‐Claude Potier, Benoı̂t Delatour — 2007
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• Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s DiseaseAmanda L. Wright, Raphael Zinn, Barbara Hohensinn — 2013

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