Long‐term follow‐up of patients with NAFLD and elevated liver enzymes
Explore this paper's citation graph
Summary
It is concluded that nonalcoholic fatty liver disease with elevated liver enzymes is associated with a clinically significant risk of developing end‐stage liver disease and Survival is lower in patients with NASH, and most NAFLD patients will develop diabetes or impaired glucose tolerance in the long term.
- Type
- article
- Published
- 2006-10-01
- Cited by
- 2,377
- References
- 26
- OpenAlex
- https://openalex.org/W1969295126
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7568443
Keywords
Medicine, Internal medicine, Nonalcoholic fatty liver disease, Gastroenterology, Liver biopsy
References
- The natural history of nonalcoholic fatty liver disease: a clinical histopathological study
- Semiquantitative evaluation overestimates the degree of steatosis in liver biopsies: a comparison to stereological point counting
- Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
- The natural history of nonalcoholic fatty liver disease: a population-based cohort study.
- Elevated AST or ALT to nonalcoholic fatty liver disease: accurate predictor of disease prevalence?
- Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity.
- Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States.
- The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies.
- Long term prognosis of fatty liver: risk of chronic liver disease and death
- One-Year Intense Nutritional Counseling Results in Histological Improvement in Patients with Nonalcoholic Steatohepatitis: A Pilot Study
- The clinical significance of slightly to moderately increased liver transaminase values in asymptomatic patients.
- The prevalence and etiology of elevated aminotransferase levels in the United States
- Nonalcoholic steatohepatitis: a study of 49 patients.
- Natural history of nonalcoholic steathepatitis: A longitudinal study of repeat liver biopsies
- Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions
- Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study
- The natural history of nonalcoholic fatty liver: A follow‐up study
- Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
- Sampling variability of liver biopsy in nonalcoholic fatty liver disease.
- Liver fibrosis in overweight patients.
Cited by
- Treatment of non-alcoholic fatty liver disease: can we already face the epidemic?
- Etiological features of cirrhosis inpatients in Beijing, China
- Recent developments in liver pathology.
- The de ritis ratio: the test of time.
- Contrast-enhanced computed tomography for the diagnosis of fatty liver: prospective study with same-day biopsy used as the reference standard
- Oxidative stress is independently associated with non-alcoholic fatty liver disease (NAFLD) in subjects with and without type 2 diabetes.
- Transcriptional Profile of Genes Involved in Oxidative Stress and Antioxidant Defense in a Dietary Murine Model of Steatohepatitis
- Investigating the role of lipocalin-2 as a diagnostic indicator for nonalcoholic steatohepatitis in a fructose-induced rat fatty liver model: First experimental studies
- Management of nonalcoholic fatty liver disease: a 60-year-old man with probable nonalcoholic fatty liver disease: weight reduction, liver biopsy, or both?
- The changing liver transplant waitlist: an emerging liver purgatory?
- Effect of resveratrol on experimental non-alcoholic steatohepatitis.
- Fibrosis in Nonalcoholic Fatty Liver Disease: Mechanisms and Clinical Implications
- Serum &bgr;-trophin level as a new marker for noninvasive assessment of nonalcoholic fatty liver disease and liver fibrosis
- Statin use and the risk of hepatocellular carcinoma in patients at high risk: A nationwide nested case-control study.
- Epigenetics: An emerging field in the pathogenesis of nonalcoholic fatty liver disease.
- Controversies in the Diagnosis and Management of NAFLD and NASH.
- Pediatric nonalcoholic fatty liver disease, metabolic syndrome and cardiovascular risk.
- [Non-alcoholic fatty liver disease].
- Noninvasive biomarkers for the screening of fibrosis, steatosis and steatohepatitis in patients with metabolic risk factors: FibroTest-FibroMax experience.
- Measurement of the coronary flow velocity reserve in patients with non-alcoholic fatty liver disease.
Related papers
- Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease.
- STUDY OF CELL MODELS OF HEPG2 STEATOSIS AND STEATOHEPATITIS VIABILITY
- Comparison of the Diagnostic Performance of Steatosis Indices for Discrimination of CT-Diagnosed Metabolic Dysfunction-Associated Fatty Liver Disease
- Are Steatosis and Steatohepatitis Triggers of Hepatic Fibrogenesis
- Review article: is non‐alcoholic fatty liver disease a spectrum, or are steatosis and non‐alcoholic steatohepatitis distinct conditions?
- 1232 XANTHOHUMOL IMPROVES GLUCOSE TOLERANCE AND INHIBITS HEPATIC STEATOSIS, INFLAMMATION AND FIBROGENESIS IN A MURINE MODEL OF NON-ALCOHOLIC STEATOHEPATITIS
- Non-alcoholic steatohepatitis
- Categorization and complication of non-alcoholic fatty liver disease
- Mo1015 Liver Function Breath Tests for Differentiation of Steatohepatitis From Simple Fatty Liver in Patients With Non-Alcoholic Fatty Liver Disease