Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions
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Summary
There are no systems for grading necroinflammatory activity or for staging fibrosis as exist for various other forms of chronic liver disease and this study proposes a grading and staging system that reflects the unique histological features of nonalcoholic steatohepatitis.
- Type
- article
- Published
- 1999-09-01
- Cited by
- 3,990
- References
- 29
- Access
- Open access
- OpenAlex
- https://openalex.org/W2087829753
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5268656
Keywords
Medicine, Steatohepatitis, Steatosis, Fibrosis, Cirrhosis
References
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- REVIEW: Nonalcoholic steatohepatitis
- Histological grading and staging of chronic hepatitis.
- Orthotopic Liver Transplantation: A Pathological Study of 63 Serial Liver Biopsies from 17 Patients with Special Reference to the Diagnostic Features and Natural History of Rejection
- Intra-observer and inter-observer variation in the histopathological assessment of chronic viral hepatitis.
- Methotrexate guidelines--revised.
- Two cases from the spectrum of nonalcoholic steatohepatitis.
- The natural history of nonalcoholic steatohepatitis: A follow‐up study of forty‐two patients for up to 21 years
- Hemosiderosis in cirrhosis: a study of 447 native livers.
- Nonalcoholic steatohepatitis: a study of 49 patients.
- Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis.
- Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
- Association between alcoholism and increased hepatic iron stores.
Cited by
- Treatment strategies in nonalcoholic fatty liver disease
- Non‐invasive markers to predict the liver fibrosis in non‐alcoholic fatty liver disease
- Proposal of a new staging and grading system of the liver for primary biliary cirrhosis
- Measurement of liver fat content using selective saturation at 3.0 T
- Influence of cannabis use on severity of hepatitis C disease.
- Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease
- Liver HCV-antigens and steatosis in chronic hepatitis C: role of different genotypes.
- Intramitochondrial crystalline inclusions in nonalcoholic steatohepatitis
- The de ritis ratio: the test of time.
- Adipocyte fatty acid binding protein levels relate to inflammation and fibrosis in nonalcoholic fatty liver disease
- Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning.
- Down-regulation of SREBP-1c is associated with the development of burned-out NASH.
- Controlled attenuation parameter (CAP): a novel VCTE™ guided ultrasonic attenuation measurement for the evaluation of hepatic steatosis: preliminary study and validation in a cohort of patients with chronic liver disease from various causes.
- Transcriptional Profile of Genes Involved in Oxidative Stress and Antioxidant Defense in a Dietary Murine Model of Steatohepatitis
- Peroxisome proliferators-activated receptor γ2 Pro12Ala variant is associated with body mass index in non-alcoholic fatty liver disease patients
- Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications
- Hepatic steatosis in hepatitis B virus infected patients: Meta‐analysis of risk factors and comparison with hepatitis C infected patients
- NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA
- Diagnosis and Evaluation of Nonalcoholic Fatty Liver Disease
- Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity.
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