Cellular bioterrorism: how Brucella corrupts macrophage physiology to promote invasion and proliferation.
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Summary
Small steps have been taken in defining and understanding the virulence factors of Brucella used in macrophage subversion, but further investigation is required to fully explain virulence and persistence.
- Type
- review
- Published
- 2005-03-01
- Cited by
- 85
- References
- 100
- OpenAlex
- https://openalex.org/W1969050107
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40069645
Keywords
Brucella, Phagolysosome, Virulence, Macrophage, Microbiology
References
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- Diminished T lymphocyte proliferative response to polyclonal mitogens in acute brucellosis patients
- Brucella abortus Lipopolysaccharide in Murine Peritoneal Macrophages Acts as a Down-Regulator of T Cell Activation1
- Control of IL-12 and IFN-gamma production in response to live or dead bacteria by TNF and other factors.
- Specific signaling pathways triggered by IL-2 in human V gamma 9V delta 2 T cells: an amalgamation of NK and alpha beta T cell signaling.
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- Lysosomal accumulation and recycling of lipopolysaccharide to the cell surface of murine macrophages, an in vitro and in vivo study.
- Brucella species release a specific, protease-sensitive, inhibitor of TNF-alpha expression, active on human macrophage-like cells.
- Subversion and Utilization of the Host Cell Cyclic Adenosine 5′-Monophosphate/Protein Kinase A Pathway by Brucella During Macrophage Infection1
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- Antigenic S-type lipopolysaccharide of Brucella abortus 1119-3
- Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.
- A beneficial aspect of a CB1 cannabinoid receptor antagonist: SR141716A is a potent inhibitor of macrophage infection by the intracellular pathogen Brucella suis
- Transposon-Derived Brucella abortusRough Mutants Are Attenuated and Exhibit Reduced Intracellular Survival
- The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides
- Incidence and control of brucellosis in the Near East region.
- ER-mediated phagocytosis: a new membrane for new functions
Cited by
- Francisella Targets Cholesterol-Rich Host Cell Membrane Domains for Entry into Macrophages1
- Intracellular Trafficking of MHC-I in Normal and HIV-1 Nef Expressing Cells.
- Lipopolysaccharide of Coxiella burnetii.
- Immune response triggered by Brucella abortus following infection or vaccination.
- Análisis in silico de los genes del operón virB de Brucella canis aisladas de caninos de criaderos en el área metropolitana del Valle de Aburrá (Antioquia, Colombia)
- Evaluation of antimicrobial effect of hops extracts on intramacrophages Brucella abortus and B. melitensis
- Chronic Brucellosis Patients Retain Low Frequency of CD4+ T-Lymphocytes Expressing CD25 and CD28 after Escherichia coli LPS Stimulation of PHA-Cultured PBMCs
- A Novel Trafficking Signal within the HLA-C Cytoplasmic Tail Allows Regulated Expression upon Differentiation of Macrophages1
- Molecular insights into bacteroid development during Rhizobium-legume symbiosis.
- Early transcriptional responses of internalization defective Brucella abortus mutants in professional phagocytes, RAW 264.7
- Cell-mediated immunity in human brucellosis.
- Characterization of Biological Activities of Brucella melitensis Lipopolysaccharide
- CD80/CD28 co‐stimulation in human brucellosis
- Induction of protective immunity against brucellosis in mice by vaccination with a combination of naloxone, alum, and heat-killed Brucella melitensis 16 M.
- Antigen-Specific Acquired Immunity in Human Brucellosis: Implications for Diagnosis, Prognosis, and Vaccine Development
- The role of the vacB gene in the pathogenesis of Brucella abortus.
- Molecular cloning, expression and characterization of programmed cell death 10 from sheep (Ovis aries).
- Host‐cell lipid rafts: a safe door for micro‐organisms?
- Deep-Sequencing Analysis of the Mouse Transcriptome Response to Infection with Brucella melitensis Strains of Differing Virulence
- Frequencies of CD4+ T Regulatory Cells and their CD25high and FoxP3high Subsets Augment in Peripheral Blood of Patients with Acute and Chronic Brucellosis
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