The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing
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Summary
Ciprofloxacin treatment influenced the abundance of about a third of the bacterial taxa in the gut, decreasing the taxonomic richness, diversity, and evenness of the community, and support the hypothesis of functional redundancy in the human gut microbiota.
- Type
- article
- Published
- 2008-11-01
- Cited by
- 2,382
- References
- 95
- Access
- Open access
- OpenAlex
- https://openalex.org/W1967821667
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:634741
Keywords
Biology, Pyrosequencing, UniFrac, Metagenomics, Gut flora
References
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- Use of 16S rRNA Gene-Targeted Group-Specific Primers for Real-Time PCR Analysis of Predominant Bacteria in Human Feces
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- Massively parallel tag sequencing reveals the complexity of anaerobic marine protistan communities
- Comparing the microbiota of the cystic fibrosis lung and human gut
- Unravelling the effects of the environment and host genotype on the gut microbiome
- Intestinal microbiota in human health and disease: the impact of probiotics
- Impact of antibiotic use, alternative therapies and inflammation on the intestinal microbiota
- Gut microbial colonisation in premature neonates predicts neonatal sepsis
- Analysis of the Cystic Fibrosis Lung Microbiota via Serial Illumina Sequencing of Bacterial 16S rRNA Hypervariable Regions
- Diagnosis of Clostridium difficile Infection: an Ongoing Conundrum for Clinicians and for Clinical Laboratories
- Intestinal colonization: How key microbial players become established in this dynamic process
- In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens.
- Impact of Targeted Specific Antibiotic Delivery for Gut Microbiota Modulation on High-Fructose-Fed Rats
- Fecal microbiome analysis as a diagnostic test for diverticulitis
- Improving the genetic representation of rare taxa within complex microbial communities using DNA normalization methods
- Probiotics or antibiotics: future challenges in medicine.
- Bacterial diversity in native habitats of the medicinal fungus Ophiocordyceps sinensis on Tibetan Plateau as determined using Illumina sequencing data.
- Comparison of the fecal microbiota of dholes high-throughput Illumina sequencing of the V3–V4 region of the 16S rRNA gene
- Improving the microbial community reconstruction at the genus level by multiple 16S rRNA regions.
- Changes in the bacterial microbiome of patients with chronic rhinosinusitis after endoscopic sinus surgery
- Rapid infectious disease identification by next-generation DNA sequencing.
- Import and spread of extended-spectrum β-lactamase-producing Enterobacteriaceae by international travellers (COMBAT study): a prospective, multicentre cohort study.
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