Applications of the Morris water maze in the study of learning and memory.
Explore this paper's citation graph
Summary
Lesions in distinct brain regions like hippocampus, striatum, basal forebrain, cerebellum and cerebral cortex were shown to impair MWM performance, but disconnecting rather than destroying brain regions relevant for spatial learning may impair M WM performance as well.
- Type
- review
- Published
- 2001-08-01
- Cited by
- 2,060
- References
- 485
- OpenAlex
- https://openalex.org/W1967061503
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2651456
Keywords
Morris water navigation task, Neuroscience, Hippocampus, Neurocognitive, Psychology
References
- Variable-interval probe test as a tool for repeated measurements of spatial memory in the water maze.
- Learning Set Spatial Navigation Performance in Three Mouse Strains
- Synaptic plasticity, place cells and spatial memory: study with second generation knockouts.
- Severe spatial navigation deficit in the Morris water maze after single high dose of neonatal x-ray irradiation in the rat.
- The GABA(B) receptor antagonist CGP36742 attenuates the baclofen- and scopolamine-induced deficit in Morris water maze task in rats.
- Comparison of the behavior of the curly tail and CBA mouse on a neurologic scale.
- Behavioral and neuroanatomical consequences of chronic ethanol intake and withdrawal.
- Cerebellar contribution to spatial event processing: characterization of procedural learning
- Neonatal Handling and Environmental Enrichment Effects on Emotionality, Novelty/Reward Seeking, and Age-Related Cognitive and Hippocampal Impairments: Focus on the Roman Rat Lines
- Animal models in stroke.
- Cholinergic modulation of spatial learning in mice in a Morris-type water maze.
- The disturbance of water-maze task performance in mice with EMC-D virus infection.
- Behavioural neuroscience : a practical approach
- The Neurobiological Basis of Memory and Behavior
- Nimodipine prevents medial septal lesion-induced performance deficits in the Morris water maze
- The Saturation Debate
- Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
- Memory: From Mind to Molecules
- Spatial event processing.
- The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro
Cited by
- Presynaptic regulation of neurotransmitter release in the cortex of aged rats with differential memory impairments.
- Soy isoflavones improve spatial delayed matching-to-place performance and reduce cholinergic neuron loss in elderly male rats.
- Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration.
- A brief, but repeated, swimming protocol is sufficient to overcome amyloid β‐protein inhibition of hippocampal long‐term potentiation
- Hippocampal-dependent learning requires a functional circadian system
- Methylphenidate affects memory, brain-derived neurotrophic factor immunocontent and brain acetylcholinesterase activity in the rat.
- Amygdala activation and GABAergic gene expression in hippocampal sub-regions at the interplay of stress and spatial learning
- Identification of aminopyridazine-derived antineuroinflammatory agents effective in an Alzheimer's mouse model.
- Value of water mazes for assessing spatial and egocentric learning and memory in rodent basic research and regulatory studies.
- Repetitive Mild Traumatic Brain Injury in the Developing Brain: Effects on Long-Term Functional Outcome and Neuropathology
- Effects of novel tacrine-related cholinesterase inhibitors in the reversal of 3-quinuclidinyl benzilate-induced cognitive deficit in rats--Is there a potential for Alzheimer's disease treatment?
- Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity
- Postconditioning Effectively Prevents Trimethyltin Induced Neuronal Damage in the Rat Brain.
- Intracerebroventricular injection of Aβ1-42 combined with two-vessel occlusion accelerate Alzheimer's disease development in rats.
- The effects of safranal, a constitute of saffron, and metformin on spatial learning and memory impairments in type-1 diabetic rats: behavioral and hippocampal histopathological and biochemical evaluations.
- Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood
- Capsaicin Ameliorates Stress-Induced Alzheimer's Disease-Like Pathological and Cognitive Impairments in Rats
- Role of central cannabinoid receptors in cerebellar dependent learning
- Previous Spatial Memory Training and Nicotine Administration Alleviates Cognitive Deficits Produced by Medial Frontal Cortex Lesions in Rats.
- The Poreh Nonverbal Memory Test
Related papers
- Inhibitory effect of lactuside B on TRPM7 mRNA expression in hippocampus and striatum in cerebral ischemic rats
- CHANGE IN VISUAL EXPERIENCE IMPAIRS RAT’S SPATIAL LEARNING IN MORRIS WATER MAZE
- The study on learning and memory ability and some amino acid content in specific brain regions of rats
- Mice are not little rats: species differences in a one‐day water maze task
- Copper suppresses hippocampus LTP in the rat, but does not alter learning or memory in the morris water maze.
- Effects of the size of the morris water tank on spatial discrimination learning in the CFW1 mouse.
- Comparison of Learning and Memory Abilities among Three Species of Mice Tested in Morris Water Maze
- Effect of sub-chronic exposure to deltamethrin on spatial learning and memory in mice
- The influence of orally administered docosahexaenoic acid on cognitive ability in aged mice.
- Cognitive function changes in response to expression of glucocorticoid recepmr from rat hippocampus after traumatic brain injury