Targeting the interleukin-15 system in rheumatoid arthritis.
Explore this paper's citation graph
- Type
- letter
- Published
- 2005-09-01
- Cited by
- 28
- References
- 21
- OpenAlex
- https://openalex.org/W1966163740
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43611507
Keywords
Rheumatoid arthritis, Medicine, Immunology, Interleukin, Cytokine
References
- Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC.
- Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology.
- Humanized antibody directed to the IL-2 receptor beta-chain prolongs primate cardiac allograft survival.
- Interleukin 15: biology and relevance to human disease.
- The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis
- Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo.
- Control of homeostasis of CD8+ memory T cells by opposing cytokines.
- Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study.
- Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.
- The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.
- IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation.
- Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis
- IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice.
- Targeting the IL-15 receptor with an antagonist IL-15 mutant/Fc gamma2a protein blocks delayed-type hypersensitivity.
- Role of cytokines in rheumatoid arthritis.
- Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model.
- The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens.
- Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice
- IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients
- Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model
Cited by
- Refractory coeliac disease
- Complications of coeliac disease.
- Refractory celiac disease
- Analysis of knee flexion characteristics and how they alter with the onset of knee osteoarthritis: a case control study
- E. coli expression and purification of human and cynomolgus IL-15.
- Biological Therapies for Rheumatoid Arthritis: Progress to Date
- New cytokine targets in inflammatory rheumatic diseases.
- Inhibition of TGF-beta signaling by IL-15: a new role for IL-15 in the loss of immune homeostasis in celiac disease.
- Refractory Celiac Disease: Epidemiology and Clinical Manifestations
- New therapeutics in rheumatoid arthritis.
- IL-12 Rapidly Alters the Functional Profile of Tumor-Associated and Tumor-Infiltrating Macrophages In Vitro and In Vivo1
- Refractory celiac disease.
- Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity.
- Targeting Memory T Cells in Type 1 Diabetes
- Interleukin 15: A key cytokine for immunotherapy.
- Interleukin-15 as a potential new target in Sjögren's syndrome-associated inflammation.
- Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability
- Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis
- Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization.
- The Effect of Hypertonic Dextrose Injection on the Control of Pain Associated with Knee Osteoarthritis
Related papers
- Genentech taps Affimed’s antibodies
- KOMPLIKASI REGIONAL ANESTESI PADA PEDIATRIK
- Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria
- Cardiac retransplantation in children.
- PD-09.06: Third kidney transplants: surgical aspects
- Avaliacao hemodinamica sequencial em transplante de coracao
- Thoracoscopic discectomy and fusion in the treatment of spinal deformities
- [Hepatic retransplant and acute Budd Chiari syndrome. Case report].