Effects of somatostatin on inositol-1,4,5-trisphosphate content in mouse spleen lymphocytes.
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Summary
It was found that the exposure of mouse spleen lymphocytes in vitro to SS sharply diminished their IP3 level, and the inhibition of phosphatydyloinositol (PI) breakdown was suggested as one of the mechanisms of the physiological SS action.
- Type
- article
- Published
- 1992-04-01
- Cited by
- 8
- References
- 13
- OpenAlex
- https://openalex.org/W1965318332
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40731318
Keywords
Inositol, In vitro, Somatostatin, Spleen, Internal medicine
References
- Effect of somatostatin on the proliferation of mouse spleen lymphocytes in vitro.
- Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.
- Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. I. An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin.
- Inositol trisphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influx in Xenopus laevis oocytes.
- G proteins and the mechanism of action of hormones, neurotransmitters, and autocrine and paracrine regulatory factors.
- Somatostatin and its analog enhance the formation of human leukocyte migration inhibiting factor: further evidence for immunomodulatory action of somatostatin.
- Immunomodulatory Action of Somatostatin
- In Vitro Studies of Immunoregulation by Substance P and Somatostatin
- Regulation of calcium influx across the plasma membrane of the human T-leukemic cell line, JURKAT: dependence on a rise in cytosolic free calcium can be dissociated from formation of inositol phosphates.
- Activation of Gi-like proteins, a receptor-independent effect of kinins in mast cells.
- Diazepam inhibits proliferation of the mouse spleen lymphocytes in vitro.
- Somatostatin — An Antiproliferative Hormone?
- Involvement of calcium channels in control of the pituitary tumoral cell proliferation in vitro
Cited by
- An update on somatostatin receptor signaling in native systems and new insights on their pathophysiology.
- Angiopeptin, a somatostatin analogue, inhibits rat coronary artery and aorta smooth muscle cell proliferation induced by the thromboxane A2 mimetic U46619.
- Immunosuppressive and antiproliferative effects of somatostatin analog SMS 201-995.
- Effects of new somatostatin analogs on the cell proliferation of colonic crypts and colonic cancers in rats.
- Effect of somatostatin on the mass accumulation of inositol-1,4,5-trisphosphate in rat hypothalamus, striatum, frontoparietal cortex and hippocampus.
- Inhibitory effect of diazepam on muscarinic receptor‐stimulated inositol 1,4,5‐trisphosphate production in rat parotid acinar cells
- Comparison of functional profiles at human recombinant somatostatin sst2 receptor: simultaneous determination of intracellular Ca2+ and luciferase expression in CHO‐K1 cells
- Effect of , ; omatostatin on the mass accumulation of inositol-1 , 4 , 5-trisphosphate in rat hypothalamus , striatum , frontoparietal cortex and hippocampus
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