Aggregatibacter actinomycetemcomitans GroEL Protein Promotes Conversion of Human CD4+ T Cells into IFNγ IL10 Producing Tbet+ Th1 Cells
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Summary
The results suggest that rAaGroEL protein affects CD4+ T cells to differentiate into IFNγ IL10-secreting T-bet+ Th1 cells.
- Type
- article
- Published
- 2012-11-12
- Cited by
- 19
- References
- 29
- Access
- Open access
- OpenAlex
- https://openalex.org/W1964224895
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1822087
Keywords
IL-2 receptor, GroEL, CD8, Aggregatibacter actinomycetemcomitans, Biology
References
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- Characterization of serum antibody to Actinobacillus actinomycetemcomitans GroEL-like protein in periodontitis patients and healthy subjects.
- Molecular characterization of the early activation antigen CD69: A type II membrane glycoprotein related to a family of natural killer cell activation antigens
- IL-10 production by CD4+ effector T cells: a mechanism for self-regulation
- Effect of adjuvants on immune response and protective immunity elicited by recombinant Hsp60 (GroEL) of Salmonella typhi against S. typhi infection
- Separation of Leucocytes: Improved Cell Purity by Fine Adjustments of Gradient Medium Density and Osmolality
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- Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
- Identification of a T cell subset capable of both IFN-gamma and IL-10 secretion in patients with chronic Borrelia burgdorferi infection.
- Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
- Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells.
- Type I chaperonins: not all are created equal
- Stress Wars: the Direct Role of Host and Bacterial Molecular Chaperones in Bacterial Infection
- T-cell, antibody, and cytokine responses to homologs of the 60-kilodalton heat shock protein in Helicobacter pylori infection
Cited by
- Pathogen manipulation of cIL-10 signaling pathways: opportunities for vaccine development?
- Aggregatibacter actinomycetemcomitans, a potent immunoregulator of the periodontal host defense system and alveolar bone homeostasis
- Gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems
- Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells
- Endogenous heat shock protein GroEL of A. actinomycetemcomitans preferentially targets primary human CD8+ T cells
- Heat shock protein complex vaccines induce antibodies against Neisseria meningitidis via a MyD88-independent mechanism.
- IL12, IL10, IFNγ and TNFα Expression in Human Primary Monocytes Stimulated with Bacterial Heat Shock GroEL (Hsp64) Protein
- Moonlight chaperonade. Interview by Sophia Häfner.
- Activation of TRIF-dependent and independent immune responses by neisserial heat shock protein complex vaccines
- Tannerella forsythia GroEL induces inflammatory bone resorption and synergizes with interleukin‐17
- Bacterial Heat Shock Protein GroEL (Hsp64) Exerts Immunoregulatory Effects on T Cells by Utilizing Apoptosis
- The Aggregatibacter actinomycetemcomitans heat shock protein GroEL interacts directly with human peripheral blood T cells
- Oral pathogenesis of Aggregatibacter actinomycetemcomitans.
- Analysis of cell surface and intranuclear markers on non-stimulated human PBMC using mass cytometry
- Les nouvelles approches de l'analyse multi-paramétrique en cytométrie de masse : caractérisation des cellules réservoirs du VIH
- Caractérisation des réponses immunitaires chez les patients atteints de myopathies auto-immunes idiopathiques
- Plant-derived galactolipids enhance specific antibody production and induce class-switch as vaccine adjuvant.
- Antibacterial Activity, Antiadherence Activity, Antioxidant Activity, and Molecular Docking Analysis of Arab Rose (Rosa Damascena) Extract on Periodontopathic Bacteria: Porphyromonas Gingivalis and Aggregatibacter Actinomycetemcomitans - An In vitro Study
- Plant-derived galactolipids enhance specific antibody production and induce class-switch as vaccine adjuvant
- Heat Shock Proteins and Periodontitis – Cross-Reaction Between Bacterial and Human HSP in Periodontal Infection Linking with Cardiovascular Diseases
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