A Lethal de Novo Mutation in the Middle Domain of the Dynamin-related GTPase Drp1 Impairs Higher Order Assembly and Mitochondrial Division*

Keywords

Mitochondrial fission, GTPase, Mitochondrion, Biology, Cell biology

References

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• Formation of elongated giant mitochondria in DFO‐induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1Young‐Sil Yoon, Dong‐Sun Yoon, In Kyoung Lim — 2006
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• Mitochondria: Dynamic Organelles in Disease, Aging, and DevelopmentDavid C. Chan — 2006
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• Regulation of mitochondrial fusion and division.Kara L. Cerveny, Yasushi Tamura, Zhongyan Zhang — 2007
• The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses.Zheng Li, Ken-Ichi Okamoto, Yasunori Hayashi — 2004
• Dimeric Dnm1-G385D Interacts with Mdv1 on Mitochondria and Can Be Stimulated to Assemble into Fission Complexes Containing Mdv1 and Fis1*Debjani Bhar, Mary Anne Karren, Markus Babst — 2006
• Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteinsBalaji Prakash, Gerrit J. K. Praefcke, Louis Renault — 2000
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• Mitochondrial Fission and Fusion Mediators, hFis1 and OPA1, Modulate Cellular Senescence*Seung-Min Lee, Seon‐Yong Jeong, Wonchung Lim — 2007

Cited by

• Mitochondrial Membrane Dynamics and Inherited Optic Neuropathies.Anna Matysek-Jędrych — 2017
• Peroxisome interactions and cross-talk with other subcellular compartments in animal cells.Michael Schrader, Sandra Grille, H. Dariush Fahimi — 2013
• Dynamin-Related Protein 1 as a therapeutic target in cardiac arrestWillard W. Sharp — 2015
• The Roles of SUMO in Metabolic RegulationElena Kamynina, Patrick J. Stover — 2017
• Posttranslational regulation of protein function and stability at the mitochondria and beyondShanna K Nifoussi — 2010
• Mitochondrien als Kraftwerk der β-ZelleSimone Baltrusch, F Reinhardt, Markus Tiedge — 2015
• How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenarioMacarena S. Arrázola, Carmen Silva-Álvarez, Nibaldo C. Inestrosa — 2015
• Peroxisome morphology in pathology.Michael Schrader, Inês Gomes Castro, H. Dariush Fahimi — 2012
• Metabolic Stress and Disorders Related to Alterations in Mitochondrial Fission or FusionMansi Babbar, M. Saeed Sheikh — 2013
• Heterogeneous nuclear ribonucleoprotein A1 post-transcriptionally regulates Drp1 expression in neuroblastoma cellsSo Jung Park, Heejin Lee, Doo Shin Jo — 2015
• Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiationUlf Dettmer, Andrew J Newman, Frank Soldner — 2015
• Proliferation and fission of peroxisomes - An update.Michael Schrader, Joseph L. Costello, Luís F. Godinho — 2016
• The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1Raymond Liu, David C. Chan — 2015
• Mécanodétection des forces hémodynamiques lors du développement endocardique chez l'espèce Danio rerioÉmilie Heckel — 2013
• Mitochondrial Genetics and Optic Neuropathy.Janey L. Wiggs — 2015
• Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fissionJian Zhao, Tong Liu, Shaobo Jin — 2011
• Purification, crystallization and X-ray diffraction analysis of human dynamin-related protein 1 GTPase-GED fusion protein.Eva Klinglmayr, Julia Wenger, Sandra Mayr — 2012
• In vivo functions of Drp1: Lessons learned from yeast genetics and mouse knockoutsHiromi Sesaki, Yoshihiro Adachi, Yusuke Kageyama — 2013
• The power of yeast to model diseases of the powerhouse of the cellSteven M. Claypool — 2013
• A designed point mutant in Fis1 disrupts dimerization and mitochondrial fissionJonathan P. B. Lees, Cara Marie Manlandro, Lora K. Picton — 2012

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