In vivo inhibition of cyclin B degradation and induction of cell-cycle arrest in mammalian cells by the neutral cysteine protease inhibitor N-acetylleucylleucylnorleucinal.
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Summary
Cyclin B degradation fails to occur, and histone H1 kinase remains activated for the duration of mitotic arrest at all ALLN concentrations, and Histone H2 kinase activity remains elevated during mitotic Arrest.
- Type
- article
- Published
- 1993-04-15
- Cited by
- 96
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1963641700
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26049248
Keywords
Cyclin B, Mitosis, Cell biology, Cyclin B1, Biology
References
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