Competitive binding of viral E2 protein and mammalian core-binding factor to transcriptional control sequences of human papillomavirus type 8 and bovine papillomavirus type 1
Explore this paper's citation graph
Summary
Competition of CBF and E2 protein for DNA binding was shown for both human papillomavirus type 8 and bovine papillomevirus type 1, and may indicate that repression by E2 is due to competitive binding of viral and cellular proteins.
- Type
- article
- Published
- 1997-10-01
- Cited by
- 13
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W1960364031
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25996317
Keywords
Biology, Bovine papillomavirus, Binding site, Transcription factor, Psychological repression
References
- Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2.
- The bovine papillomavirus 1 E2 protein contains two activation domains: one that interacts with TBP and another that functions after TBP binding.
- Short protocols in molecular biology
- Low-affinity E2-binding site mediates downmodulation of E2 transactivation of the human papillomavirus type 8 late promoter
- A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor
- E2 represses the late gene promoter of human papillomavirus type 8 at high concentrations by interfering with cellular factors
- Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 protein
- Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer
- Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer cores
- Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions
- Sequence specificity of the core-binding factor
- The E2 trans-activator can act as a repressor by interfering with a cellular transcription factor.
- Bovine papillomavirus contains multiple transforming genes.
- PEBP2—A Modulator of Polyoma DNA Replication
- Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation.
- Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells.
- Human epidermis reconstructed by culture: is it "normal"?
- Transcriptional repression of eukaryotic promoters.
- Constitutive transcriptional activator of Epidermodysplasia verruciformis-associated human papillomavirus 8.
- Negative and positive factors determine the activity of the polyoma virus enhancer alpha domain in undifferentiated and differentiated cell types.
Cited by
- HPV protein/peptide vaccines: from animal models to clinical trials.
- The determinants for the native activities of the bovine papillomavirus type 1 E2 protein are separable
- The Human Papillomavirus Type 8 E2 Protein Suppresses β4-Integrin Expression in Primary Human Keratinocytes
- SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b
- A new cellular factor recognizes E2 binding sites of papillomaviruses which mediate transcriptional repression by E2.
- The Papillomavirus E2 Proteins
- RUNX1 Permits E4orf6-Directed Nuclear Localization of the Adenovirus E1B-55K Protein and Associates with Centers of Viral DNA and RNA Synthesis
- Cooperative Activation of Human Papillomavirus Type 8 Gene Expression by the E2 Protein and the Cellular Coactivator p300
- Human Papillomavirus Type 8 E2 Protein Unravels JunB/Fra-1 as an Activator of the β4-Integrin Gene in Human Keratinocytes
- The E6 Protein of the Cutaneous Human Papillomavirus Type 8 Can Stimulate the Viral Early and Late Promoters by Distinct Mechanisms
- Posttranslationale Kontrolle des zellulären Transkriptionsfaktors PBF/ZNF395
- p 300 the E 2 Protein and the Cellular Coactivator Papillomavirus Type 8 Gene Expression by Cooperative Activation of Human
- E 4 orf 6-Directed Nuclear Localization of the Adenovirus E 1 B-55 K Protein and Associates with Centers of Viral DNA and RNA Synthesis
Related papers
- A new transcription factor family associated with human leukemias.
- Cooperative DNA binding of the bovine papillomavirus E2 transcriptional activator is antagonized by truncated E2 polypeptides
- Enhanced transcriptional activation by E2 proteins from the oncogenic human papillomaviruses
- Trans activation by the bovine papillomavirus E2 protein in Saccharomyces cerevisiae
- DNA-Prot: Identification of DNA Binding Proteins from Protein Sequence Information using Random Forest
- Cellular Topoisomerase I Modulates Origin Binding by Bovine Papillomavirus Type 1 E1
- DNA structure and flexibility in the sequence-specific binding of papillomavirus E2 proteins.
- DNA-binding activity of papillomavirus proteins