A New Crystal Structure of Deoxyhypusine Synthase Reveals the Configuration of the Active Enzyme and of an Enzyme·NAD·Inhibitor Ternary Complex*

Keywords

NAD+ kinase, Enzyme, Ternary complex, ATP synthase, Ternary operation

References

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Cited by

• Piperidones with activity against Plasmodium falciparumPatricia S. Hill, Thomas G. Greco — 2006
• In silico Design, Synthesis, and Screening of Novel Deoxyhypusine Synthase Inhibitors Targeting HIV‐1 ReplicationLúcia Nagib — 2014
• Cloning, expression and functional characterization of deoxyhypusine synthase from the pathogenic fungus Fusarium graminearum Schwabe (teleomorph Gibberella zeae), wheat (Triticum aestivum L.) and maize (Zea mays L.)Mayada Woriedh — 2011
• Cloning, expression and functional activity of deoxyhypusine synthase from Plasmodium vivaxJ.T. Njuguna, Nassar Marwa, Achim Hoerauf — 2006
• Cryptosporidium parvum has an active hypusine biosynthesis pathwayNimisha Mittal, Marie Morada, Pankaj Tripathi — 2014
• Allosteric Activation of Trypanosomatid Deoxyhypusine Synthase by a Catalytically Dead ParalogSuong Nguyen, Deuan C. Jones, Susan Wyllie — 2013
• The hypusine-containing translation factor eIF5AThomas Dever, Erik Gutierrez, Byung‐Sik Shin — 2014
• Guanylated diamines, triamines, and polyamines: chemistry and biological properties.Daniele Castagnolo, Silvia Schenone, Maurizio Botta — 2011
• Molecular cloning and functional expression of bovine deoxyhypusine hydroxylase cDNA and homologs.Jenq‐Kuen Huang, Yalun Cui, Chieh-Hua Chen — 2007
• Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modificationEdith C. Wolff, Kee Ryeon Kang, Kim Ys — 2007
• Deoxyhypusine Synthase Promotes Differentiation and Proliferation of T Helper Type 1 (Th1) Cells in Autoimmune Diabetes*Stephanie C. Colvin, Bernhard Maier, David L. Morris — 2013
• The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria—inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthaseSabine Specht, Salem Ramadan Sarite, Ilona Hauber — 2008
• Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells.Yurika Nishiki, Adeola F. Adewola, Masayuki Hatanaka — 2013
• The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).Myung Hee Park — 2006
• Preventing Fusarium head blight of wheat and cob rot of maize by inhibition of fungal deoxyhypusine synthase.Mayada Woriedh, Ilona Hauber, Ana Lilia Martínez-Rocha — 2011
• Post-translational Modification by β-Lysylation Is Required for Activity of Escherichia coli Elongation Factor P (EF-P)*Jong‐Hwan Park, Hans E. Johansson, Hiroyuki Aoki — 2011
• The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylationKan Kobayashi, Assaf Katz, Andrei Rajkovic — 2014
• Molecular modeling of the human eukaryotic translation initiation factor 5A (eIF5A) based on spectroscopic and computational analyses.Cláudio M. Costa-Neto, Lucas T. Parreiras‐e‐Silva, Roberto Ruller — 2006
• Cloning and Expression Profile of Deoxyhypusine Snyhtase Gene and Deoxyhypusine Hydroxylase Gene in Silkworm, Bombyx moriWang Geng-xian, Yang‐Hu Sima, Sheng-xiang Zhang — 2009
• Effects of novel C-methylated spermidine analogs on cell growth via hypusination of eukaryotic translation initiation factor 5AMervi T. Hyvönen, Tuomo A. Keinänen, М. А. Хомутов — 2011

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