DNA Methylation, Cancer Susceptibility, and Nutrient Interactions
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Summary
Dietary factors that are involved in one-carbon metabolism provide the most compelling data for the interaction of nutrients and DNA methylation because they influence the supply of methyl groups, and therefore the biochemical pathways of methylation processes.
- Type
- review
- Published
- 2004-11-01
- Cited by
- 423
- References
- 80
- OpenAlex
- https://openalex.org/W1945361080
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14488154
Keywords
DNA methylation, Methylation, Epigenetics, Biology, Carcinogenesis
References
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- Mechanisms of DNA damage, DNA hypomethylation, and tumor progression in the folate/methyl-deficient rat model of hepatocarcinogenesis.
- Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.
- Methylenetetrahydrofolate reductase, alcohol dehydrogenase, diet, and risk of colorectal adenomas.
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- Genomic hypomethylation is specific for preneoplastic liver in folate/methyl deficient rats and does not occur in non-target tissues.
- Reduced breast cancer risk with increasing serum folate in a case-control study of the C677T genotype of the methylenetetrahydrofolate reductase gene.
- DNA methylation analysis: a powerful new tool for lung cancer diagnosis
Cited by
- Using nutrigenomics to evaluate apoptosis as a preemptive target in cancer prevention.
- Vitamin B6 deficiency, genome instability and cancer.
- Genome-wide screening for understanding the role of DNA methylation in colorectal cancer.
- MicroRNA-137 promoter methylation as an etiologic and prognostic biomarker for squamous cell carcinoma of the head and neck
- Epigenetic transcriptional repression of tumor suppresor genes and its reversion by drugs.
- [S-adenosyl L-methionine in CNS diseases].
- Diet, epigenetics, and cancer.
- Animal models of epigenetic regulation in neuropsychiatric disorders.
- [Influence of environmental factors on DNA methylation].
- A computational model for colon cancer dynamics
- Effect Of Folate Deficiency On Expression Of Proteins On The Mtor Signaling Pathway In The Brain Of C57/bl6 Mice
- Diet, lifestyle, heritable factors and colorectal carcinogenesis: associations with histopathological and molecular endpoints
- The Epigenetic Effects of Prenatal Folate Supplementation on Male CD1 Mouse Fetuses Exposed in utero to Arsenic
- Allergen-induced regulatory properties of the CD4+CD25+ subset in cord blood and possible implications on the post-natal tolerance induction
- Nutrients and Epigenetics
- Molecular mechanisms and physiology of disease
- Effect of isothiocyanates and selenium on antioxidant enzyme expression and DNA methylation in colon cancer cells in vitro
- Super DNAging-New insights into DNA integrity, genome stability and telomeres in the oldest old.
- Animal models of maternal nutrition and altered offspring bone structure--bone development across the lifecourse.
- DNA Methylation and its Association with Prenatal Exposures and Pregnancy Outcomes
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