IL-19 Induced Th2 Cytokines and Was Up-Regulated in Asthma Patients1
Explore this paper's citation graph
Summary
Results demonstrated that IL-19 up-regulates Th2 cytokines on activated T cells and might play an important role in the pathogenesis of asthma.
- Type
- article
- Published
- 2004-12-01
- Cited by
- 124
- References
- 25
- Access
- Open access
- OpenAlex
- https://openalex.org/W1918093686
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26776888
Keywords
Immunology, Asthma, Pathogenesis, Interleukin 4, House dust mite
References
- Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GMCSF.
- Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into Th1 effectors.
- IL-4 directs the development of Th2-like helper effectors.
- IL-4 is required to generate and sustain in vivo IgE responses.
- Repeated intratracheal inoculation of house dust mite (Dermatophagoides farinae) induces pulmonary eosinophilic inflammation and IgE antibody production in mice.
- Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells
- Human interleukin-19 and its receptor: a potential role in the induction of Th2 responses.
- Impaired development of Th2 cells in IL-13-deficient mice.
- Involvement of IL-5 in a murine model of allergic pulmonary inflammation: prophylactic and therapeutic effect of an anti-IL-5 antibody.
- Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
- Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes.
- Identification of functional domains on human interleukin 10.
- Disruption of the murine IL-4 gene blocks Th2 cytokine responses
- Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of T Cell Development in Transgenic Mice Expressing IL-13
- Interleukin-13: central mediator of allergic asthma.
- Interleukin 10: a novel stimulatory factor for mast cells and their progenitors
- Eosinophil infiltration precedes development of airway hyperreactivity and mucosal exudation after intranasal administration of interleukin-5 to mice.
- The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
- A Single Amino Acid Determines the Immunostimulatory Activity of Interleukin 10
- Interleukin-10 Is a Natural Suppressor of Cytokine Production and Inflammation in a Murine Model of Allergic Bronchopulmonary Aspergillosis
Cited by
- Induction of interleukin-19 and interleukin-22 after cardiac surgery with cardiopulmonary bypass.
- IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity
- Immune Regulation and Protective Immunity during Helminth and Protozoan Infections
- The role of T lymphocytes in asthma.
- IL-20 Receptor 2 Signaling Down-Regulates Antigen-Specific T Cell Responses1
- Respiratory syncytial virus induced recurrent wheeze: genetic determinants and preventive glucocorticosteroid treatment
- Astrocytes Produce IL-19 in Response to Bacterial Challenge and are Sensitive to the Immunosuppressive Effects of this IL-10 Family Member
- Expansion of Parasite-Specific CD4+ and CD8+ T Cells Expressing IL-10 Superfamily Cytokine Members and Their Regulation in Human Lymphatic Filariasis
- Targeting interleukins to treat severe asthma
- IL-19 IS INVOLVED IN THE PATHOGENESIS OF ENDOTOXIC SHOCK
- Detection of IL-20 and its receptors on psoriatic skin.
- Promoter analysis of interleukin 19.
- Induced interleukin-19 contributes to cell-mediated immunosuppression in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.
- Interferon‐λ1 (interleukin‐29) preferentially down‐regulates interleukin‐13 over other T helper type 2 cytokine responses in vitro
- Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases.
- Interleukin-19: multiple roles in immune regulation and disease.
- Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
- [Regulation of mucosal immunity by airway epithelium: the interleukin-17A paradigm].
- Role of some biomarkers in placental malaria in women living in Yaoundé, Cameroon.
- Inhibiting Interleukin-19 Activity Ameliorates Esophageal Squamous Cell Carcinoma Progression
Related papers
- The major allergen of the house dust mite, Dermatophagoides pteronyssinus, is synthesized and secreted into its alimentary canal.
- Der f 16: a novel gelsolin‐related molecule identified as an allergen from the house dust mite, Dermatophagoides farinae 1
- Physicochemical characterization of a major protein allergen, Der p I, from the house dust mite, Dermatophagoides pteronyssinus. Amino acid analysis and circular dichroism studies.
- Identification of a novel cofilin-related molecule (Der f 31) as an allergen from Dermatophagoides farinae.
- The house-dust mite (Dermatophagoides pteronyssinus) and the allergens it produces. Identity with the house-dust allergen
- Molecular, Structural and Immunological Characterization of Der p 18, a Chitinase-Like House Dust Mite Allergen
- IL-25 induces expression of Th2 inflammatory factor by nuocyte in asthma of mouse
- Decreased expression of P-glycoprotein in interleukin-1β and interleukin-6 treated rat hepatocytes
- Exploration of the Serum Interleukin-17 and Interleukin-27 Expression Levels in Children with Bronchial Asthma and Their Correlation with Indicators of Lung Function
- For adults with moderate to severe asthma, how do anti-interleukin-13 (IL-13) and anti-interleukin-4 (IL-4) agents compare with placebo?