The role of T lymphocytes in asthma.
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Summary
Efficacy of cyclosporin and anti-CD4 treatment in chronic severe asthma argues for continued T-cell involvement, but whether remodeling contributes to pathology inaccessible to antiinflammatory treatment or T- cell immunotherapy remains an important question.
- Type
- review
- Published
- 2006-01-01
- Cited by
- 146
- References
- 82
- OpenAlex
- https://openalex.org/W1496660230
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20869060
Keywords
FOXP3, Immunology, Immunotherapy, Medicine, Asthma
References
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- IL-11 Selectively Inhibits Aeroallergen-Induced Pulmonary Eosinophilia and Th2 Cytokine Production1
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- 294 Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: Comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness
- Trial of cyclosporin in corticosteroid-dependent chronic severe asthma.
- Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma.
- Pathophysiology of severe asthma.
- T lymphocyte activation in acute severe asthma.
- Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
Cited by
- How much do we know about atopic asthma: where are we now?
- Thymic stromal lymphopoietin and its downstream networks in severe asthma
- Stem Cell and Biological Interventions to treat Allergic Airway Disease
- Thymic Stromal Lymphopoietin: Expression and Secretion by Airway Epithelium as a Function of Genotype
- Caffeic acid phenethyl ester inhibits nuclear factor‐κB and protein kinase B signalling pathways and induces caspase‐3 expression in primary human CD4+ T cells
- The essential role of SIGIRR/TIR8 in regulation of Th2 immune response
- Pathophysiology of allergic inflammation
- Fisiopatologia da asma grave
- Hypersensitivity Response to Aspergillus fumigatus: Immunopathogenesis of Allergic Airway Disease and Pulmonary Arterial Remodeling.
- A network modeling approach to analysis of the Th2-memory responses underlying human atopic disease
- Stratified approaches to the treatment of asthma
- γ-Secretase Inhibitor Alleviates Acute Airway Inflammation of Allergic Asthma in Mice by Downregulating Th17 Cell Differentiation
- Early clinical evaluation of the intranasal TLR7 agonist GSK2245035: Use of translational biomarkers to guide dosing and confirm target engagement
- The role of CRAC channel in asthma.
- A potential immunopathogenic role for reduced IL-35 expression in allergic asthma
- Resolution of Der p1-Induced Allergic Airway Inflammation Is Dependent on CD4+CD25+Foxp3+ Regulatory Cells1
- An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy?
- Exposição precoce ao poluente 1,2-naftoquinona (1,2-NQ) e a susceptibilidade diferencial à inflamação pulmonar em camundongos C57BL/6 machos e fêmeas.
- Autocrine Regulation of IL-21 Production in Human T Lymphocytes1
- microRNA profiling and target identification in a mouse model for allergic asthma
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