Genetic and molecular analysis of wings apart-like (wapl), a gene controlling heterochromatin organization in Drosophila melanogaster.
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Summary
Analysis of the role of wapl in meiotic chromosome segregation in females and whether wapl modulates position-effect variegation (PEV) showed that wapl is a dominant suppressor of both white and Stubblevariegation, while it is a weak enhancer of brown variegations.
- Type
- article
- Published
- 2000-04-01
- Cited by
- 104
- References
- 93
- Access
- Open access
- OpenAlex
- https://openalex.org/W1917475571
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16770026
Keywords
Biology, Genetics, Heterochromatin, Drosophila melanogaster, Meiosis
References
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- Molecular Analysis of a Cytochrome P450 Gene of Family 4 on the Drosophila X Chromosome
- Cluster of Cytochrome P450 Genes on the X Chromosome of Drosophila melanogaster
- Unfolding the mysteries of heterochromatin.
- Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II.
- Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes.
Cited by
- Unscheduled overexpression of human WAPL promotes chromosomal instability.
- HMMerThread: Detecting Remote, Functional Conserved Domains in Entire Genomes by Combining Relaxed Sequence-Database Searches with Fold Recognition
- Visual behavior: mice run from overhead danger.
- The mouse oocyte as a model in reproductive toxicology studies
- Cohesin Complexes in Polytene Chromosomes of Drosophila melanogaster Are Located in Interbands
- Investigation of the role of Pds5 and Wapl in sister chromatid separation in mammalian cells
- The Role of Cohesin Associated Factors, Pds5,Scc3, and Wpl1 during Cohesion Establishmentand Maintenance in Budding Yeast
- Cohesin complexes and sister chromatid cohesion in mammalian meiosis.
- Mechanisms of sister chromatid pairing.
- Chromatin structure and the regulation of gene expression: the lessons of PEV in Drosophila.
- Effect of the Suppressor of Underreplication (SuUR) gene on position-effect variegation silencing in Drosophila melanogaster.
- Identification of chromosome inheritance modifiers in Drosophila melanogaster.
- Recombinogenic effects of suppressors of position-effect variegation in Drosophila.
- Effects of 3-methylcholanthrene on the transcriptional activity and mRNA accumulation of the oncogene hWAPL.
- Wapl is an essential regulator of chromatin structure and chromosome segregation
- Expression of various types of alternatively spliced WAPL transcripts in human cervical epithelia.
- The sister bonding of duplicated chromosomes
- Chromosome biology: Wapl spreads its wings.
- Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.
- How cohesin and CTCF cooperate in regulating gene expression
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