High- and low-dose interferon alfa-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190.
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Summary
The results of the intergroup E1690 trial demonstrate an RFS benefit of IFNalpha2b that is dose-dependent and significant for HDI by Cox multivariable analysis.
- Type
- article
- Published
- 2000-06-12
- Cited by
- 876
- References
- 13
- OpenAlex
- https://openalex.org/W1908752382
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11855812
Keywords
Medicine, Melanoma, Internal medicine, Randomized controlled trial, Gastroenterology
References
- The Large Sample Distribution of the Weighted Log Rank Statistic Under General Local Alternatives
- Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.
- Critical analysis of the current American Joint Committee on Cancer staging system for cutaneous melanoma and proposal of a new staging system.
- Adjuvant interferon alfa-2a treatment in resected primary stage II cutaneous melanoma. Austrian Malignant Melanoma Cooperative Group.
- A Comparison of Prognostic Factors and Surgical Results in 1,786 Patients with Localized (Stage I) Melanoma Treated in Alabama, USA, and New South Wales, Australia
- A Multifactorial Analysis of Melanoma: III. Prognostic Factors in Melanoma Patients with Lymph Node Metastases (Stage II)
- A Multifactorial Analysis of Melanoma: Prognostic Histopathological Features Comparing Clark's and Breslow's Staging Methods
- Model predicting survival in stage I melanoma based on tumor progression.
- Quality-of-life-adjusted survival analysis of interferon alfa-2b adjuvant treatment of high-risk resected cutaneous melanoma: an Eastern Cooperative Oncology Group study.
- Randomized, surgical adjuvant clinical trial of recombinant interferon alfa-2a in selected patients with malignant melanoma.
- Economic analysis of adjuvant interferon alfa-2b in high-risk melanoma based on projections from Eastern Cooperative Oncology Group 1684.
- Evaluation of efficacy of adjuvant rIFN-alfa-2a in melanoma patients with regional nodal metastases (abstract)
Cited by
- The Sunbelt Melanoma Trial
- Diagnostik und adjuvante Therapie des malignen Melanoms
- Biological and clinical developments in melanoma vaccines
- Cytokines: interleukin and interferon therapy in dermatology
- Immunization of Patients with Malignant Melanoma with Autologous CD34+ Cell-Derived Dendritic Cells Transduced Ex Vivo with a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene: A Phase I Trial
- Melanoma in children and adolescents.
- New pharmacokinetic and pharmacodynamic tools for interferon-alpha (IFN-α) treatment of human cancer
- Pegylated interferons: prospects for the use in the adjuvant and palliative therapy of metastatic melanoma.
- Aktuelle Aspekte der adjuvanten Therapie des malignen Melanoms
- Relaxed Poisson cure rate models
- Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy
- Adjuvant therapy for resected stage III melanoma patients: high-dose interferon-alpha versus ipilimumab combined with kinases inhibitors.
- Interferón en el tratamiento del melanoma
- Advances in Adjuvant Therapy: Potential for Prognostic and Predictive Biomarkers
- Cutaneous melanoma: Taiwan experience and literature review.
- Adjuvante Interferontherapie beim Hochrisikomelanom
- Cancer immunotherapy: current status and future directions.
- Pulmonary and cutaneous sarcoidosis associated with interferon therapy for melanoma.
- Malignes Melanom
- Adjuvant therapy of melanoma.
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