Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts
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Summary
The response of the transin gene to EGF appears to require de novo protein synthesis, and treatment of cells with the microfilament-disrupting agent cytochalasin B, but not the microtubule-disruption agent colcemid, resulted in an increase in transin RNA levels, suggesting a role for the cytoskeleton in control of transin genes expression.
- Type
- article
- Published
- 1986-05-01
- Cited by
- 288
- References
- 62
- Access
- Open access
- OpenAlex
- https://openalex.org/W1908718505
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26057865
Keywords
Biology, Molecular biology, Epidermal growth factor, Gene expression, RNA
References
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- Making sense out of LINES: long interspersed repeat sequences in mammalian genomes
- Rapid similarity searches of nucleic acid and protein data banks.
Cited by
- Molecular oncogenetics of metastasis.
- A gene for rabbit synovial cell collagenase: member of a family of metalloproteinases that degrade the connective tissue matrix.
- Gene expression of interstitial collagenase (matrix metalloproteinase 1) in gastrointestinal tract cancers
- Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells
- Isolation, characterization, and expression of feline stromelysin-1 in naturally developing tumors in cats.
- Extracellular matrix metalloproteinases in tumor invasion and metastasis.
- A role for cytokines as regulators of hepatic fibrogenesis
- Transforming Proteins of DNA Tumor Viruses
- jun: oncogene and transcription factor.
- Role of type IV collagenases in human breast cancer.
- Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton.
- Expression of matrix metalloproteinases and inhibitor by human trabecular meshwork.
- Stromal-epithelial interaction in type IV collagenase expression and activation: The role in cancer metastasis.
- c-ets1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans.
- The matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) genes. Transcriptional and posttranscriptional regulation, signal transduction and cell-type-specific expression.
- Structure and expression of the cDNA encoding human neutrophil collagenase.
- AP-1 regulation during malignant progression of mouse keratinocyte cells
- Advances in Growth Hormone and Growth Factor Research
- Epithelial-Mesenchymal Interactions in Cancer
- Expression of metalloproteinases in human prostate carcinoma and their role in invasion and metastasis.
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