Specific stimulation of actin gene transcription by epidermal growth factor and cycloheximide.
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Summary
Run-off transcription experiments demonstrate that the simultaneous addition of EGF and cycloheximide produced a synergistic effect on actin sequences in both steady-state nuclear and polysomal RNA, and suggest the existence of a specific labile repressor of actin gene transcription.
- Type
- article
- Published
- 1984-12-01
- Cited by
- 154
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1967116429
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13099203
Keywords
Cycloheximide, Biology, Transcription (linguistics), Molecular biology, Cell biology
References
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- Regulation of EGF receptor and transforming growth factor-alpha expression.
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- Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells
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