Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase

Keywords

Mutant, Biology, Mutagenesis, Escherichia coli, O-6-methylguanine-DNA methyltransferase

References

• Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage.Ian Teo, Barbara Sedgwick, Bruce Demple — 1984
• Base-pairing properties of O6-methylguanine in template DNA during in vitro DNA replication.Elizabeth T. Snow, Robert S. Foote, Soma Mitra — 1984
• Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agentsPenelope A. Jeggo — 1979
• Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNADiane E. Shevell, A M Abou-Zamzam, Bruce Demple — 1988
• Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.Bruce Demple, A Jacobsson, Mariann Olsson — 1982
• Experiments in molecular geneticsJeffrey H Miller — 1972
• Functional domains and methyl acceptor sites of the Escherichia coli ada protein.Barbara Sedgwick, Peter Robins, Nicholas F. Totty — 1988
• Characterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimuriumG. William Rebeck, C M Smith, D L Goad — 1989
• Phasmid vectors for identification of genes by complementation of Escherichia coli mutantsStephen J. Elledge, Graham C. Walker — 1985
• Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agentsPaul F. Schendel, Martine Defais, Penelope A. Jeggo — 1978
• Nonenzymatic methylation of DNA by the intracellular methyl group donor S‐adenosyl‐L‐methionine is a potentially mutagenic reaction.Björn Rydberg, Tomas Lindahl — 1982
• Multiple species of Bacillus subtilis DNA alkyltransferase involved in the adaptive response to simple alkylating agentsFumiko Morohoshi, N. Munakata — 1987
• Escherichia coli gene induction by alkylation treatment.Michael R. Volkert, Dinh C. Nguyen, K. Christopher Beard — 1986
• A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.Mitchell Singer, Teresa Baker, Gavin R. Schnitzler — 1989
• Mutation spectrum in Escherichia coli DNA mismatch repair deficient (mutH) strain.C. Rewinski, Martin Marinus — 1987
• Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.Mark C. Wilkinson, Philip M. Potter, Lynn Cawkwell — 1989
• A set of lacZ mutations in Escherichia coli that allow rapid detection of each of the six base substitutions.Claire G. Cupples, Jeffrey H Miller — 1989
• A constitutive O6-methylguanine-DNA methyltransferase of Rhizobium meliloti.A. Kaufman, Graham C. Walker — 1990
• Efficiency of the adaptive response of Escherichia coli to alkylating agentsJohn Cairns — 1980
• Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coli.Tommie V. McCarthy, Tomas Lindahl — 1985

Cited by

• The influence of DNA glycosylases on spontaneous mutation.José Luis Murga Martínez — 1998
• Contribution of E. coli AlkA, TagA glycosylases and UvrABC-excinuclease in MMS mutagenesis.Takashi Tsuchiya — 2001
• Structure, function, and inhibition of O6-alkylguanine-DNA alkyltransferase.Anthony E. Pegg, M. Eileen Dolan, R C Moschel — 1995
• Nanostructures d'ADN supportées sur billes magnétiques de nouveaux outils senseurs des systèmes de réparation de l'ADNG. Gines — 2013
• Impacte dels sistemes de reparació de lesions produïdes per agents alquilants en la virulència de Salmonella enterica ser. TyphimuriumGerard Àlvarez Juste — 2010
• Identification of SoxS-Regulated Genes inSalmonella enterica Serovar TyphimuriumPablo J. Pomposiello, Bruce Demple — 2000
• Adaptive mutagenesis: a process that generates almost exclusively beneficial mutationsBarry G. Hall — 2004
• A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine.Tina M. Crone, A E Pegg — 1993
• Alteration of the conserved residue tyrosine-158 to histidine renders human O6-alkylguanine-DNA alkyltransferase insensitive to the inhibitor O6-benzylguanine.Meng Xu‐Welliver, José Leitão, Sreenivas Kanugula — 1999
• The origin of point mutations in human tumor cells.B S Strauss — 1992
• Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanineMasami Yamada, Barbara Sedgwick, Toshio Sofuni — 1995
• Escherichia coli DNA glycosylase Mug: a growth‐regulated enzyme required for mutation avoidance in stationary‐phase cellsSanath K. Mokkapati, Antonio R. Fernández de Henestrosa, Ashok S. Bhagwat — 2001
• Overexpression of enzymes that repair endogenous damage to DNA.Guido Fròsina — 2000
• Base excision repair.Lisiane B. Meira, Nicholas E. Burgis, Leona D. Samson — 2005
• DNA repair and protection mechanisms in Escherichia coli and Mycobacterium tuberculosisPamela Di Pasquale — 2014
• The Escherichia coli AlkB protein protects human cells against alkylation-induced toxicityBao‐Ji Chen, Patrick Carroll, Leona D. Samson — 1994
• Tumor-Associated Mutations in O6-Methylguanine DNA-Methyltransferase (MGMT) Reduce DNA Repair FunctionalityKristy L. Lamb, Yanfeng Liu, Kimiko Ishiguro — 2012
• Alkylation damage in mammalian cells : an analysis of the mutagenic potential of O4-methylthymine adductsKara B. Altshuler — 1994
• Directed mutation: between unicorns and goatsPatricia L. Foster — 1992
• Engineering human DNA alkyltransferases for gene therapy using random sequence mutagenesis.Lance P. Encell, Melissa M. Coates, Lawrence A. Loeb — 1998

Related papers

• The correlation between promoter methylation status and the expression level of O6-methylguanine-DNA methyltransferase in recurrent glioma.Tomohide Suzuki, Mitsutoshi Nakada, Yuya Yoshida — 2011
• Экспрессия MGMT в опухолевой ткани при лечении пациентов с нейроэндокринными опухолями режимами на основе АранозыПолозкова Светлана Александровна, Е. В. Степанова, А. Ю. Барышников — 2013
• O6-Methylguanine-DNA methyltransferase in human cells.Daniel B. Yarosh, Mary Rice, Rufus S. Day — 1984
• Understanding and manipulating O6-methylguanine-DNA methyltransferase expression.Russell O. Pieper — 1997
• A constitutive O6-methylguanine-DNA methyltransferase of Rhizobium meliloti.A. Kaufman, Graham C. Walker — 1990
• Progression of O6-methylguanine-DNA methyltransferase and temozolomide resistance in cancer researchGuan Jiang, Aijun Jiang, Yong Xin — 2014
• Methyltransferase in human non-small cell lung cancerLijun Miao — 2010
• Progression of O 6 -methylguanine-DNA methyltransferase and temozolomide resistance in cancer researchGuan JiangAi-Jun, JiangYong Xin, Lian-Tao LiQian — 2014
• Heterogeneity of Human Glioblastoma: Glutathione-S-Transferase and Methylguanine-MethyltransferaseLucienne Juillerat‐Jeanneret, Catherine Chapuis Bernasconi, Charlotte Bricod — 2008