Nonenzymatic methylation of DNA by the intracellular methyl group donor S‐adenosyl‐L‐methionine is a potentially mutagenic reaction.

Keywords

Biology, Methylation, DNA methylation, Methionine, DNA

References

• Molecular Mechanisms for Repair of DNAPhilip C. Hanawalt, R. B. Setlow — 1975

Cited by

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• O6-Methylguanine induces altered proteins at the level of transcription in human cellsDominica Contreras y López de Ayala — 2010
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• Preparation of covalently linked complexes between DNA and O(6)-alkylguanine-DNA alkyltransferase using interstrand cross-linked DNA.António Luis Pinto da Costa — 2013
• Intrinsic properties of a KlenTaq DNA polymerase mutant with enhanced substrate specificity determined by X-ray structure analysisAndreas Schnur — 2009
• Studies of the Rev1 protein and its role in the replication of damaged DNAJohn M. Pryor — 2012
• DNA modification by sulfur mustards and nitrosoureas and repair of these lesions.David B. Ludlum, Bruno Papirmeister — 1986
• Elucidating the role of Cdc25A in hypoxia-mediated cell cycle arrestQueiroz de Oliveira, Esaie Pierre — 2009
• X-ray repair cross-complementing protein 1 associated multiprotein complexes in base excision repairAudun Hanssen‐Bauer — 2012
• Historical origins of current concepts of carcinogenesis.P.D. Lawley — 1994
• Mechanisms of DNA Damage Recognition in Mammalian CellsHanspeter Naegeli — 1997
• Impacte dels sistemes de reparació de lesions produïdes per agents alquilants en la virulència de Salmonella enterica ser. TyphimuriumGerard Àlvarez Juste — 2010
• Biological implications of the mechanism of action of human DNA (cytosine-5)methyltransferase.Steven S. Smith — 1994
• Regulation of repair of alkylation damage in mammalian genomes.Sankar Mitra, Bernd Kaina — 1993
• Base Excision Repair in ChromatinA. Prasad — 2008
• N6‐methyladenine functions as a potential epigenetic mark in eukaryotesQinmiao Sun, Shoujun Huang, Xiaona Wang — 2015
• Transcriptional response of O⁶-methylguanine methyltransferase deficient yeast to methyl-N-nitro-N-nitrosoguanidine (MNNG)A. Rao — 2004
• SERIES: Genomic instability in cancer Balancing repair and tolerance of DNA damage caused by alkylating agentsDragony Fu, Jennifer A. Calvo, Leona D. Samson — 2012
• Repair of DNA Containing Small Heterologous Sequences by Escherichia Coli: a DissertationBreck O. Parker — 1991
• The mutational spectrum of the HPRT gene from human T cells in vivo shares a significant concordant set of hot spots with MNNG-treated human cells.Aoy Tomita‐Mitchell, Losee L. Ling, Curtis L. Glover — 2003

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