Using linkage maps to correct and scaffold de novo genome assemblies: methods, challenges, and computational tools

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Summary

The methodology behind integrating de novo assemblies and genetic linkage maps is summarized, the current challenges are outlined, the available software tools are reviewed, and new mapping technologies are discussed.

Type
review
Published
2015-06-19
Cited by
140
References
88
Access
Open access

Keywords

Linkage (software), Genome, Computational biology, DNA sequencing, Sequence assembly

References

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