ProFAT: a web-based tool for the functional annotation of protein sequences
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Summary
By employing sensitive database search programs as well as exploiting the functional information associated with database sequences, ProFAT can detect remote, but biologically relevant relationships between proteins and will assist researchers in the prediction of protein function based on remote homologies.
- Type
- article
- Published
- 2006-10-23
- Cited by
- 10
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W1876675804
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9139308
Keywords
Annotation, Computer science, Biological database, Protein structure database, Context (archaeology)
References
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- Protein structure comparison by alignment of distance matrices.
- Predicting coiled coils from protein sequences
- A new approach to protein fold recognition
- Successful recognition of protein folds using threading methods biased by sequence similarity and predicted secondary structure
- Cpc1, a Chlamydomonas central pair protein with an adenylate kinase domain
- OntoBlast function: from sequence similarities directly to potential functional annotations by ontology terms
- An intronic insertion in KPL2 results in aberrant splicing and causes the immotile short-tail sperm defect in the pig.
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- Multiple sequence alignment with the Clustal series of programs
- An algorithm for suffix stripping
Cited by
- HMMerThread: Detecting Remote, Functional Conserved Domains in Entire Genomes by Combining Relaxed Sequence-Database Searches with Fold Recognition
- Machine Learning Approaches to Bioinformatics
- Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox.
- Improving classification in protein structure databases using text mining
- Conformational adaptability of Redbeta during DNA annealing and implications for its structural relationship with Rad52.
- A transparent collaborative framework for efficient data analysis and knowledge annotation on the web
- An In Silico Approach for Function Prediction of Hypothetical Proteins of Mycobacterium laprae TN
- Cold-Induced Reprogramming of Subcutaneous White Adipose Tissue Assessed by Single-Cell and Single-Nucleus RNA Sequencing
- Conformational Adaptability of Red β during DNA Annealing and Implications for Its Structural Relationship with Rad 52
- Bioinformatic Tools for the Search of Disease-Associated Variations
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