Functional heterogeneity in the basophil cell lineage
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Summary
The recent identification of phenotypic and functional heterogeneity within murine and human basophil populations is discussed and it is discussed how these findings may explain the context-dependent influence of basophils on either the propagation, regulation or effector phases of Th2 cytokine-associated inflammation.
- Type
- review
- Published
- 2012-01-01
- Cited by
- 45
- References
- 71
- Access
- Open access
- OpenAlex
- https://openalex.org/W1857406570
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34294952
Keywords
Basophil, Biology, Effector, Immunology, Inflammation
References
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Cited by
- The biology of thymic stromal lymphopoietin (TSLP)
- Effector Cells and Mechanisms in Chronic Spontaneous Urticaria
- Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel
- Basophils: historical reflections and perspectives.
- TSLP-elicited basophil responses can mediate the pathogenesis of eosinophilic esophagitis
- Th9/IL-9 Profile in Human Echinococcosis: Their Involvement in Immune Response during Infection by Echinococcus granulosus
- Emerging Role of Human Basophil Biology in Health and Disease
- TH2, allergy and group 2 innate lymphoid cells
- Exposure to food allergens through inflamed skin promotes intestinal food allergy via the TSLP-basophil axis
- Pathogenic memory type Th2 cells in allergic inflammation.
- Receptor activating NF-κB ligand (RANKL) is a constitutive intracellular protein in resting human basophils and is strongly induced on their surface by interleukin 3.
- Basophils and skin disorders.
- Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients.
- Natural helper cell development and their role in mediating the innate Th2 inflammatory response
- Transcriptional Regulation of Mast Cell and Basophil Lineage Commitment
- Selective depletion of basophils ameliorates immunoglobulin E-mediated anaphylaxis
- The role of natural killer cells in resolution of antigen-induced inflammation
- The Role of Vitamin D in the Immune System as a Pro-survival Molecule.
- Innate immunity as the orchestrator of allergic airway inflammation and resolution in asthma.
- Granulocytes as modulators of dendritic cell function
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