Immune attack: the role of inflammation in Alzheimer disease
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Summary
As inflammation in AD primarily concerns the innate immune system — unlike in 'typical' neuroinflammatory diseases such as multiple sclerosis and encephalitides — the concept of neuroinflammation in AD may need refinement.
- Type
- review
- Published
- 2015-05-20
- Cited by
- 2,005
- References
- 225
- OpenAlex
- https://openalex.org/W1841850981
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6116253
Keywords
Inflammation, Immune system, Disease, Medicine, Immunology
References
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Cited by
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- Overview of Traumatic Brain Injury: An Immunological Context
- Alzheimer's disease: Innate immunity gone awry?
- Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers
- Should We Stop Saying 'Glia' and 'Neuroinflammation'?
- Recent advances in the neurobiology and neuropharmacology of Alzheimer's disease.
- Heparan Sulfate Proteoglycans as Relays of Neuroinflammation
- Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα
- IgM response against amyloid-beta in aging: a potential peripheral protective mechanism
- Visceral fat-related systemic inflammation and the adolescent brain: a mediating role of circulating glycerophosphocholines
- Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease.
- Mesenchymal stem cells for the treatment of neurological diseases: Immunoregulation beyond neuroprotection.
- Neuroinflammatory processes in cognitive disorders: Is there a role for flavonoids and n-3 polyunsaturated fatty acids in counteracting their detrimental effects?
- Endothelial dysfunction and amyloid-β-induced neurovascular alterations
- Oleocanthal Enhances Amyloid-β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model
- The role of immunity and neuroinflammation in genetic predisposition and pathogenesis of Alzheimer’s disease
- Metabolic profiling distinguishes three subtypes of Alzheimer's disease
- Linking T cells to Alzheimer's disease: from neurodegeneration to neurorepair.
- The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease
- TMEM119 marks a subset of microglia in the human brain
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