Metabolic profiling distinguishes three subtypes of Alzheimer's disease
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Summary
It is reported that metabolic profiling reveals three Alzheimer's disease subtypes, and the involvement of zinc in multiple Alzheimer's-related metabolic processes, such as insulin resistance, chronic inflammation, ADAM10 proteolytic activity, and hormonal signaling warrants further metabolic, genetic, and epigenetic characterization.
- Type
- article
- Published
- 2015-08-01
- Cited by
- 69
- References
- 19
- Access
- Open access
- OpenAlex
- https://openalex.org/W1798009377
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5326776
Keywords
Insulin resistance, Disease, Alzheimer's disease, Dementia, Bioinformatics
References
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- Zinc Deficiency and Zinc Therapy Efficacy with Reduction of Serum Free Copper in Alzheimer's Disease
- Neuroprotective Sirtuin ratio reversed by ApoE4
- Focal cortical presentations of Alzheimer's disease.
- Function and mechanism of zinc metalloenzymes.
- Reversal of cognitive decline: A novel therapeutic program
- 1α,25-Dihydroxyvitamin D3 and Resolvin D1 Retune the Balance between Amyloid-β Phagocytosis and Inflammation in Alzheimer’s Disease Patients
- Contribution of Alzheimer disease to mortality in the United States
Cited by
- Clusters of male and female Alzheimer’s disease patients in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database
- Inhalational Alzheimer's disease: an unrecognized—and treatable—epidemic
- Reversal of cognitive decline in Alzheimer's disease
- Dose-dependent genotype effects of BDNF Val66Met polymorphism on default mode network in early stage Alzheimer's disease
- Genetics of Tinnitus: An Emerging Area for Molecular Diagnosis and Drug Development
- First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease
- Quantitative Erythrocyte Omega-3 EPA Plus DHA Levels are Related to Higher Regional Cerebral Blood Flow on Brain SPECT
- A 2-year Double-Blind RCT Follow-up Study with Fermented Papaya Preparation (FPP) Modulating Key Markers in Middle-Age Subjects with Clustered Neurodegenerative Disease-Risk Factors
- Why does Finland have the highest dementia mortality rate? Environmental factors may be generalizable.
- Framing Confusion: Dementia, Society, and History.
- Downregulation of protein phosphatase 2A by apolipoprotein E: Implications for Alzheimer's disease
- Analysis of Risk Factors for Development of Cognitive Disorders in Maintenance Hemodialysis Patients – Pilot Study
- Immune Modulation in the Treatment of Amyotrophic Lateral Sclerosis: A Review of Clinical Trials
- Exploring the Association between Alzheimer’s Disease, Oral Health, Microbial Endocrinology and Nutrition
- Heritable genotype contrast mining reveals novel gene associations specific to autism subgroups
- Alzheimer’s disease syndrome – Recognizing the complexity of dementia
- Early Candidate Urine Biomarkers for Detecting Alzheimer’s Disease Before Amyloid-β Plaque Deposition in an APP (swe)/PSEN1dE9 Transgenic Mouse Model
- Clinical Lifestyle Medicine Strategies for Preventing and Reversing Memory Loss in Alzheimer’s
- A systematic review and meta-analysis of metal concentrations in canned tuna fish in Iran and human health risk assessment.
- Critical role of mitosis in spontaneous late-onset Alzheimer’s disease; from a Shugoshin 1 cohesinopathy mouse model
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