The Cellular and Molecular Basis of Translational Immunometabolism.
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Summary
The importance of understanding and manipulating the integration of systemic and immune cell metabolism through in-depth analysis of immune cell phenotype and function in human metabolic diseases and, in parallel, of the effects of conventional metabolic drugs on immune cell differentiation and function is discussed.
- Type
- review
- Published
- 2015-09-15
- Cited by
- 186
- References
- 192
- Access
- Open access
- OpenAlex
- https://openalex.org/W1828418245
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205423112
Keywords
Immune system, Cell metabolism, Biology, Effector, Function (biology)
References
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- The Interaction of ApoA-I and ABCA1 Triggers Signal Transduction Pathways to Mediate Efflux of Cellular Lipids
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Cited by
- Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration
- Immunometabolic biomarkers of inflammation in Behçet's disease: relationship with epidemiological profile, disease activity and therapeutic regimens
- Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases
- Current topics in HIV pathogenesis, part 2: Inflammation drives a Warburg-like effect on the metabolism of HIV-infected subjects.
- Stunting correlates with high salivary and serum antibody levels after 13-valent pneumococcal conjugate vaccination of Venezuelan Amerindian children.
- Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
- Metabolic Inflammation-Differential Modulation by Dietary Constituents
- Immune biomarkers in the spectrum of childhood noncommunicable diseases.
- Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering.
- IFN‐&ggr; orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways
- Treating the host response to emerging virus diseases: lessons learned from sepsis, pneumonia, influenza and Ebola.
- Blocking Immunosuppressive Factors and Taking Advantage of the Nutrient Supply Within the Tumor Microenvironment: Pathways to Achieve Improved Cancer Immunotherapeutic Efficacy for Patients With Metastatic Melanoma
- Translating the biology of adipokines in atherosclerosis and cardiovascular diseases: Gaps and open questions.
- Symbiont-induced odorant binding proteins mediate insect host hematopoiesis
- Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals
- Immunometabolic Regulation of Interleukin-17-Producing T Helper Cells: Uncoupling New Targets for Autoimmunity
- T cell metabolism in metabolic disease-associated autoimmunity.
- The bioenergetics of inflammation: insights into obesity and type 2 diabetes
- Metabolic regulation of macrophages during tissue repair: insights from skeletal muscle regeneration
- Immunometabolism and Exercise: New avenues
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