Regulation of cholesterol-7alpha-hydroxylase: BAREly missing a SHP.
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Summary
Recent studies show there is an "FXR/SHP-independent" mechanism that also represses CYP7A1 expression, which involves the interaction of bile acids with liver macrophages, which induces the expression, and secretion of cytokines.
- Type
- article
- Published
- 2002-04-01
- Cited by
- 78
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1824181430
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37141925
Keywords
Cholesterol 7 alpha-hydroxylase, Farnesoid X receptor, Small heterodimer partner, G protein-coupled bile acid receptor, Bile acid
References
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