Mitochondria: the missing link between preconditioning and neuroprotection.
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Summary
The crucial targets and mediators by which mitochondria are integrated into neuroprotective signaling pathways that underlie preconditioning are highlighted, putting focus on mitochondrial respiratory chain and mitochondrial reactive oxygen species, mitochondrial ATP-sensitive potassium channels, mitochondrial permeability transition pore, uncoupling proteins and mitochondrial antioxidant enzyme manganese superoxide dismutase.
- Type
- review
- Published
- 2010-06-03
- Cited by
- 55
- References
- 121
- Access
- Open access
- OpenAlex
- https://openalex.org/W1814262012
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6753056
Keywords
Neuroprotection, Mitochondrion, Neurodegeneration, Ischemic preconditioning, Mitochondrial permeability transition pore
References
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- The biochemistry of apoptosis
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Cited by
- Effets sur le métabolisme énergétique mitochondrial myocardique et hépatique de la carence en donneurs de méthyles au cours de la gestation et de l'allaitement chez le raton
- Diazoxide preconditioning antagonizes cytotoxicity induced by epileptic seizures
- Novel Therapeutic Approaches to Multiple Sclerosis: Neuroprotective Drugs for Relapsing-Remitting Multiple Sclerosis
- Novel Cellular Mechanisms for Neuroprotection in Ischemic Preconditioning: A View from Inside Organelles
- Preconditioning for traumatic brain injury
- Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins.
- Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α.
- The possible impact of noise-induced Ca2+-dependent activity in the central auditory pathway: A manganese-enhanced MRI study
- Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders
- Mutant HSPB8 causes protein aggregates and a reduced mitochondrial membrane potential in dermal fibroblasts from distal hereditary motor neuropathy patients.
- Mitochondrial Biogenesis Contributes to Ischemic Neuroprotection Afforded by LPS Preconditioning
- Diazoxide Pretreatment Prevents Aβ1–42 Induced Oxidative Stress in Cholinergic Neurons Via Alleviating NOX2 Expression
- Mitochondrial Uncoupling Proteins and Oxidative Stress: Implications for Diabetes and Neurodegeneration
- KATP Channel Opener Diazoxide Prevents Neurodegeneration: A New Mechanism of Action via Antioxidative Pathway Activation
- Hyperoxia preconditioning: the next frontier in neurology?
- Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms.
- Pentoxifylline enhances the protective effects of hypertonic saline solution on liver ischemia reperfusion injury through inhibition of oxidative stress.
- Novel adenosine 5′-triphosphate-sensitive potassium channel ligands: a patent overview (2005 – 2010)
- Diazoxide Attenuates Autoimmune Encephalomyelitis and Modulates Lymphocyte Proliferation and Dendritic Cell Functionality
- Mitochondrial neuroprotection in traumatic brain injury: rationale and therapeutic strategies.
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