Purification of a new dimeric protein from Cliona vastifica sponge, which specifically blocks a non-L-type calcium channel in mouse duodenal myocytes.
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Summary
Mapacalcine was unable to block T-type calcium current in portal vein myocytes as well as voltage-dependent potassium currents and calcium-activated chloride currents in duodenal and portal vein cells and did not affect caffeine-induced calcium responses, indicating that it did not interfere with intracellular calcium stores.
- Type
- article
- Published
- 1997-06-01
- Cited by
- 15
- References
- 31
- OpenAlex
- https://openalex.org/W1798350464
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:697678
Keywords
Calcium, Calcium in biology, T-type calcium channel, Myocyte, Voltage-dependent calcium channel
References
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- Molecular diversity of voltage-dependent Ca2+ channels.
- Different types of calcium channels mediate central synaptic transmission
- Inhibition of actin polymerization by latrunculin A
- Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium
- Roles of N-type and Q-type Ca2+ channels in supporting hippocampal synaptic transmission.
- Functional expression of a rapidly inactivating neuronal calcium channel
- Angiotensin II‐activated Ca2+ entry‐induced release of Ca2+ from intracellular stores in rat portal vein myocytes
- P-type calcium channels in rat central and peripheral neurons.
- Potential‐dependent inward currents in single isolated smooth muscle cells of the rat ileum.
- Comparison of binding affinities and calcium current inhibitory effects of a 1,4-dihydropyridine derivative (PN 200-110) in vascular smooth muscle.
- The agonist effect of dihydropyridines on Ca channels
- Purification and characterization of a pore-forming protein from the marine sponge Tethya lyncurium.
- Quantitative analysis of drug-receptor interactions: I. Determination of kinetic and equilibrium properties.
- Calcium channels coupled to glutamate release identified by omega-Aga-IVA.
Cited by
- Characterization of mapacalcine-sensitive Ca(2+) channels in rat kidney.
- Mapacalcine Protects Mouse Neurons against Hypoxia by Blocking Cell Calcium Overload
- Novel voltage‐dependent non‐selective cation conductance in murine colonic myocytes
- Effects of marine organisms extracts on microtubule integrity and cell cycle progression in cultured cells
- Decreased Expression of Ryanodine Receptors Alters Calcium-induced Calcium Release Mechanism in mdx Duodenal Myocytes*
- Mapacalcine specifically blocks hypoxia-induced calcium influx in rat hepatocytes.
- Stimulation of L‐type Ca2+ Channels by Inositol Pentakis‐ and Hexakisphosphates in Rat Vascular Smooth Muscle Cells
- Distribution of mapacalcine receptors in the central nervous system of rat using the [125I]-labeled mapacalcine derivative.
- Lectins from Tropical Sponges
- Bioactive peptides from marine sources: pharmacological properties and isolation procedures.
- Ionic conductances in gastrointestinal smooth muscles and interstitial cells of Cajal.
- Production, in Pichia pastoris, of a recombinant monomeric mapacalcine, a protein with anti-ischemic properties
- Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes
- Online Publication Date: 19 January, 2012 Publisher: Asian Economic and Social Society Bioactive Compounds From Spirastrella Inconstans Against Wound Infection
- PHARMACOLOGICAL PERCEPTION OF PEPTIDES FROM MARINE SPONGE: A REVIEW Baby Joseph*, Vrundha M. Nair and S. Sujatha International Centre for Bioresources Management, Malankara Catholic College, Mariagiri, Kaliakkavilai, 629153, Kanyakumari district, Tamil Nadu, India
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