Absence of Fibroblast Growth Factor 2 Promotes Oligodendroglial Repopulation of Demyelinated White Matter
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Summary
It is demonstrated that the F GF2 genotype regulates oligodendrocyte regeneration and that FGF2 appears to inhibit oligodendedrocytes lineage differentiation during remyelination.
- Type
- article
- Published
- 2002-10-01
- Cited by
- 177
- References
- 69
- Access
- Open access
- OpenAlex
- https://openalex.org/W1790384858
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16651820
Keywords
Remyelination, Oligodendrocyte, Biology, Progenitor cell, Fibroblast growth factor
References
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- Multiple Sclerosis: Remyelination in Acute Lesions
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- Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice.
- A single intracerebral microinjection of platelet-derived growth factor (PDGF) accelerates the rate of remyelination in vivo.
- FGF modulates the PDGF-driven pathway of oligodendrocyte development.
- Gene expression in brain during cuprizone-induced demyelination and remyelination.
- Fibroblast growth factor 2 control of vascular tone
Cited by
- Remyelination strategies: New advancements toward a regenerative treatment in multiple sclerosis
- The Role of Wnt Signaling in Oligodendrocyte Development
- Fibroblast growth factors in oligodendrocyte physiology and myelin repair.
- Genetic analysis of CNS remyelination.
- The Oligodendrocyte Progenitor Response to Demyelination
- Molecular mechanisms regulating embryonic cerebral cortex development.
- The effect of aging on myelinating gene expression and oligodendrocyte cell densities
- Pharmacological approaches to intervention in hypomyelinating and demyelinating white matter pathology
- Paving the way for adequate myelination: The contribution of galectin‐3, transferrin and iron
- Enhanced Immunoreactivity for Basic Fibroblast Growth Factor (FGF2) in the Adult Rat Spinal Cord in Experimental Syringomyelia
- Synantocytes: New functions for novel NG2 expressing glia
- The role of complex gangliosides in glial cell biology
- Aberrant Growth and Differentiation of Oligodendrocyte Progenitors in Neurofibromatosis Type 1 Mutants
- The Influence of Platelet-Derived Growth Factor and Fibroblast Growth Factor 2 on Oligodendrocyte Development and Remyelination
- NG2-glia and their functions in the central nervous system
- Glia Disease and Repair-Remyelination.
- Biomaterial Approaches to Enhancing Neurorestoration after Spinal Cord Injury: Strategies for Overcoming Inherent Biological Obstacles
- Thyroid Hormone Potentially Benefits Multiple Sclerosis via Facilitating Remyelination
- The chemokine receptor CXCR2 is differentially regulated on glial cells in vivo but is not required for successful remyelination after cuprizone‐induced demyelination
- Spatial and Temporal Profiles of Growth Factor Expression during CNS Demyelination Reveal the Dynamics of Repair Priming
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