Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.
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Summary
Evidence is provided that Ad5-Delta24RGD has strong antitumor activity in malignant glioma, which can be additionally enhanced by irradiation such that the same therapeutic effect is achieved when a 10-fold lower viral dose is applied.
- Type
- article
- Published
- 2002-10-15
- Cited by
- 209
- References
- 32
- OpenAlex
- https://openalex.org/W1781724529
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39294066
Keywords
Oncolytic virus, Glioma, Cancer research, Retinoblastoma, Radiation therapy
References
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Cited by
- Oncolytic virotherapy for malignant glioma: translating laboratory insights into clinical practice
- Selective Replicating Viral Vectors
- Adenovirus targeting for gene therapy of pancreatic cancer
- Gene therapy trials for the treatment of high-grade gliomas.
- Cancer Treatment with Gene Therapy and Radiation Therapy
- Potentialisation de la virothérapie anti-tumorale basée sur des adénovirus oncolytiques dans le traitement des cancers côliques et rénaux
- Gene therapy for gastric cancer: is it promising?
- Environmental risk assessment of replication competent viral vectors in gene therapy trials
- Bioprocess design of canine adenovirus vectors for gene therapy applications
- Improving oncolytic adenoviral therapies for gastrointestinal cancers and tumor initiating cells
- Molecular Determinants of Radiation Response
- Optimisation de la radiovirothérapie en associant un traitement radio-isotopique vectorisé par un virus de la rougeole oncolytique, une radiothérapie externe et une inhibition de checkpoint kinase-1
- In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells
- Adenoviral gene therapy for non-small cell lung cancer
- ONCOLYTIC ADENOVIRUSES FOR GYNECOLOGIC CANCER
- Ras-dependent oncolysis with an adenovirus VAI mutant.
- Experimental adenovirus gene therapy for cancer patients with advanced tumors : Translational medicine from basic research to the patient's bedside
- Adenoviral gene therapy for ovarian cancer
- Gene Therapy and Virotherapy: Novel Therapeutic Approaches for Brain Tumors
- Oncolytic adenoviral therapy for glioblastoma multiforme.
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