Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.

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Summary

Evidence is provided that Ad5-Delta24RGD has strong antitumor activity in malignant glioma, which can be additionally enhanced by irradiation such that the same therapeutic effect is achieved when a 10-fold lower viral dose is applied.

Type
article
Published
2002-10-15
Cited by
209
References
32

Keywords

Oncolytic virus, Glioma, Cancer research, Retinoblastoma, Radiation therapy

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