Identification of the major phosphorylation sites of the Raf-1 kinase.
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Summary
It is found that Ser43, Ser259, and Ser621 are the major sites of Raf-1 which are phosphorylated in mammalian cells and in Sf9 insect cells infected with a recombinant baculovirus encoding human Raf- 1.
- Type
- article
- Published
- 1993-08-15
- Cited by
- 333
- References
- 4
- Access
- Open access
- OpenAlex
- https://openalex.org/W1675086682
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24833932
Keywords
Phosphorylation, Identification (biology), Kinase, Cell biology, Chemistry
References
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Cited by
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- The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors.
- The ethylene response pathway in Arabidopsis.
- Regulation of Raf‐1 activation and signalling by dephosphorylation
- Structure and activity of the atypical serine kinase Rio1
- Regulation of the Ras-MAPK pathway at the level of Ras and Raf.
- An investigation of the kinase dependent functions of CRaf
- Noninvasive Imaging of Ras Activity by Monomolecular Biosensor Based on Split-Luciferase Complementary Assay
- Stress activated MAPKs in plants
- Protein phosphorylation and signal transduction.
- Activation of Raf-1 by Ras in intact cells.
- Neuroprotective properties of sigma-1 receptor in glaucoma
- Screening for microbial inhibitors against signal transduction in Eukaryotes and Mycobacterium
- The role of D-raf in the terminal class signal transduction pathway in Drosophila melanogaster
- MAP kinase-dependent pathways in cell cycle control.
- Regulation of Raf‐1 kinase activity by the 14‐3‐3 family of proteins.
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