Molecular evidence for an ancient duplication of the entire yeast genome
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Summary
A model is proposed in which this species is a degenerate tetraploid resulting from a whole-genome duplication that occurred after the divergence of Saccharomyces from Kluyveromyces, and protein pairs derived from this duplication event make up 13% of all yeast proteins.
- Type
- article
- Published
- 1997-06-12
- Cited by
- 1,817
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W1641544182
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4307263
Keywords
Gene duplication, Biology, Saccharomyces cerevisiae, Genome, Gene
References
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- Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase.
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- Heterogeneity of Clones of Saccharomyces Derived from Haploid Ascospores.
- Evolution by Gene Duplication
- Cloning and analysis of the Kluyveromyces lactis TRP1 gene: A chromosomal locus flanked by genes encoding inorganic pyrophosphatase and histone H3
- Life with 6000 Genes
- Vertebrate evolution by interspecific hybridisation – are we polyploid?
- Two yeast chromosomes are related by a fossil duplication of their centromeric regions.
Cited by
- Resource utilization and competition among yeasts
- Genetic redundancy in vertebrates: polyploidy and persistence of genes encoding multidomain proteins.
- Inter‐ and intraspecific chromosome pattern variation in the yeast genus Kluyveromyces
- Exploring redundancy in the yeast genome: an improved strategy for use of the cre-loxP system.
- Maximum-likelihood approach for gene family evolution under functional divergence.
- Origin of the duplicated regions in the yeast genomes.
- Widespread Paleopolyploidy in Model Plant Species Inferred from Age Distributions of Duplicate Genes
- Aneuploidy and Genetic Variation in the Arabidopsis thaliana Triploid Response
- PEX Genes in Fungal Genomes: Common, Rare or Redundant
- Elusive Origins of the Extra Genes in Aspergillus oryzae
- Genomic polymorphism in the population of Candida glabrata: gene copy-number variation and chromosomal translocations.
- A prominent role for segmental duplications in modeling eukaryotic genomes.
- Inventory and Comparative Evolution of the ABC Superfamily in the Genomes of Phytophthora ramorum and Phytophthora sojae
- Transcriptional Regulation of Carbohydrate Metabolism in the Human Pathogen Candida albicans
- Saccharomyces cerevisiae Bat1 and Bat2 Aminotransferases Have Functionally Diverged from the Ancestral-Like Kluyveromyces lactis Orthologous Enzyme
- CONSERVED NONCODING SEQUENCES REGULATE STEADY-STATE mRNA LEVELS IN Arabidopsis thaliana
- KlRox1p contributes to yeast resistance to metals and is necessary for KlYCF1 expression in the presence of cadmium.
- A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways
- Genome scale metabolic modeling of the riboflavin overproducer Ashbya gossypii
- Algorithms for sequence-based reverse metabolic engineering
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